Evidence map›Paper›PMID 37352872›Full record

SynthesisBJS open2023

Global cost of postoperative ileus following abdominal surgery: meta-analysis.

Luke Traeger, Michalis Koullouros, Sergei Bedrikovetski, Hidde M Kroon, James W Moore, Tarik Sammour

Open access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BJS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 8 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 8 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Luke TraegerColorectal Unit, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0002-0327-7334
Michalis KoullourosColorectal Unit, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0001-6688-7634
Sergei BedrikovetskiColorectal Unit, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0001-9330-625X
Hidde M KroonColorectal Unit, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0002-8923-7527
James W MooreColorectal Unit, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Tarik SammourColorectal Unit, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0002-4918-8871
Royal Adelaide Hospital · AU

Funding

Colorectal Research Group ScholarshipRoyal Adelaide Hospital Research Committee DawesUniversity of Adelaide Research Training Program Stipend
6 · The paper itself

Abstract

backgroundFollowing abdominal surgery, postoperative ileus is a common complication significantly increasing patient morbidity and cost of hospital admission. This is the first systematic review aimed at determining the average global hospital cost per patient associated with postoperative ileus.

methodsA systematic search of electronic databases was performed from January 2000 to March 2023. Studies included compared patients undergoing abdominal surgery who developed postoperative ileus to those who did not, focusing on costing data. The primary outcome was the total cost of inpatient stay. Risk of bias was assessed using the Newcastle-Ottawa assessment tool. Summary meta-analysis was performed.

resultsOf the 2071 studies identified, 88 papers were assessed for full eligibility. The systematic review included nine studies (2005-2022), investigating 1 860 889 patients undergoing general, colorectal, gynaecological and urological surgery. These studies showed significant variations in the definition of postoperative ileus. Six studies were eligible for meta-analysis showing an increase of €8233 (95 per cent c.i. (5176 to 11 290), P < 0.0001, I2 = 95.5 per cent) per patient with postoperative ileus resulting in a 66.3 per cent increase in total hospital costs (95 per cent c.i. (34.8 to 97.9), P < 0.0001, I2 = 98.4 per cent). However, there was significant bias between studies. Five colorectal-surgery-specific studies showed an increase of €7242 (95 per cent c.i. (4502 to 9983), P < 0.0001, I2 = 86.0 per cent) per patient with postoperative ileus resulting in a 57.3 per cent increase in total hospital costs (95 per cent c.i. (36.3 to 78.3), P < 0.0001, I2 = 85.7 per cent).

conclusionThe global financial burden of postoperative ileus following abdominal surgery is significant. While further multicentre data using a uniform postoperative ileus definition would be useful, reducing the incidence and impact of postoperative ileus are a priority to mitigate healthcare-related costs, and improve patient outcomes.

Indexed as

Colorectal NeoplasmsDigestive System Surgical ProceduresIleusHospitalizationHumansPostoperative Complications

Identifiers

PMID37352872
PMCPMC10289829
OpenAlexW4381839266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.