ArticleNeuron2023
A neural mechanism for terminating decisions.
Article in Neuron, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 78 citations in OpenAlex.
- Behavioral demands organize a decision process into distinct yet coordinated neural representations in parietal cortex.bioRxiv : the preprint server for biology · 2026Article
- Regulation of the decision threshold by the locus coeruleus.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering.Nature neuroscience · 2026Article
- Article
- Frontal Eye Field Leads a Distributed Oculomotor Circuit for Abstract Categorical Decisions.bioRxiv : the preprint server for biology · 2026Article
- Neural correlates of perceptual decision-making in the primary somatosensory cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Macaque Area LIP Reflects Confidence-Dependent Changes in Decision Policy.bioRxiv : the preprint server for biology · 2026Article
- Live Spike Sorting of Large-scale Neural Recordings.bioRxiv : the preprint server for biology · 2026Article
- Interactions across hemispheres in prefrontal cortex reflect global cognitive processing.Nature communications · 2026Article
- Misinterpreting Electrophysiology in Human Cognitive Neuroscience.Psychophysiology · 2026Review
- Human decision-makers terminate evidence accumulation using flexible decision rules.bioRxiv : the preprint server for biology · 2026Article
- Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice.Nature communications · 2026Article
- Rhythmic sampling of multiple decision alternatives in the human brain.Nature communications · 2026Article
- How distributed is the brain-wide network that is recruited for cognition?Nature reviews. Neuroscience · 2026Review
- Article
- No Central Executive? Decision Formation Through Multi-Area Population Dynamics.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Brain-wide coordination of internal signals during decision-making.bioRxiv : the preprint server for biology · 2025Article
- Disentangling decision uncertainty and motor noise in curved movement trajectories.Journal of vision · 2025Article
- Article
- Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex.PLoS biology · 2025Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
The brain makes decisions by accumulating evidence until there is enough to stop and choose. Neural mechanisms of evidence accumulation are established in association cortex, but the site and mechanism of termination are unknown. Here, we show that the superior colliculus (SC) plays a causal role in terminating decisions, and we provide evidence for a mechanism by which this occurs. We recorded simultaneously from neurons in the lateral intraparietal area (LIP) and SC while monkeys made perceptual decisions. Despite similar trial-averaged activity, we found distinct single-trial dynamics in the two areas: LIP displayed drift-diffusion dynamics and SC displayed bursting dynamics. We hypothesized that the bursts manifest a threshold mechanism applied to signals represented in LIP to terminate the decision. Consistent with this hypothesis, SC inactivation produced behavioral effects diagnostic of an impaired threshold sensor and prolonged the buildup of activity in LIP. The results reveal the transformation from deliberation to commitment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.