ArticleStem cell reports2023
Donor perspectives on informed consent and use of biospecimens for brain organoid research.
Article in Stem cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Harnessing human tumor organoids for cancer modeling and precision therapy.Protein & cell · 2026Review
- Ethics and Regulation of Human Brain Organoid Research: Recommendations from the Asia Pacific Neuroethics Working Group.Asian bioethics review · 2026Article
- Brain Organoids: Emerging Platforms for Modern Neuroscience.Brain sciences · 2026Review
- Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation.Advanced healthcare materials · 2026Review
- Japanese attitudes toward human brain organoid research: broad support amid ethical concerns.Frontiers in genetics · 2026Article
- Modeling Alzheimer's disease with brain organoids: mechanisms, applications, and future directions.Frontiers in cell and developmental biology · 2026Review
- From Cells to Organoids: Approaches, Regulatory Mechanisms, Applications, and Challenges of Organoids.Cells · 2025Review
- The ethical aspects of human organ-on-chip models: A mapping review.Stem cell reports · 2025Review
- Transparency and ongoing communication with participants in brain organoid research: Consensus of an interdisciplinary working group.Stem cell reports · 2025Article
- Ethical considerations for advancing research using organoid models derived from the placenta.Human reproduction update · 2025Review
- Japanese attitudes toward cell donation in human brain organoid research: many oppose broad consent.Frontiers in genetics · 2025Article
- Biobanking, digital health and privacy: the choices of 1410 volunteers and neurological patients regarding limitations on use of data and biological samples, return of results and sharing.BMC medical ethics · 2024Article
- Dynamic governance: A new era for consent for stem cell research.Stem cell reports · 2024Review
- Moral considerability of brain organoids from the perspective of computational architecture.Oxford open neuroscience · 2024Article
- Ethics and regulation of neuronal optogenetics in the European Union.Pflugers Archiv : European journal of physiology · 2023Review
- Revisiting the Obligation to Share Aggregate Results with Research Participants in the Era of Open Science.Ethics & human researchArticle
- Organ Chips and Translational Research: Identifying and Examining New Ethical Issues.Ethics & human researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Debates about the ethics of human brain organoids have proceeded without the input of individuals whose brains are being modeled. Interviews with donors of biospecimens for brain organoid research revealed overall enthusiasm for brain organoids as a tool for biomedical discovery, alongside a desire for ongoing engagement with research teams to learn the results of the research, to allow transfer of decision-making authority over time, and to ensure ethical boundaries are not crossed. Future work is needed to determine the most feasible and resource-efficient way to longitudinally engage donors participating in brain organoid research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.