Evidence map›Paper›PMID 37352841›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Management of Pediatric Pneumonia: A Decade After the Pediatric Infectious Diseases Society and Infectious Diseases Society of America Guideline.

Lilliam Ambroggio, Jillian Cotter, Matthew Hall, Daniel J Shapiro, Susan C Lipsett, Adam L Hersh, Samir S Shah, Thomas V Brogan, Jeffrey S Gerber, Derek J Williams and 3 more

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lilliam AmbroggioSections of Emergency Medicine and Hospital Medicine, Children's Hospital Colorado, Department of Pediatrics, University of Colorado, Aurora, Colorado, USA.
Jillian CotterSections of Emergency Medicine and Hospital Medicine, Children's Hospital Colorado, Department of Pediatrics, University of Colorado, Aurora, Colorado, USA.
Matthew HallChildren's Hospital Association, Lenexa, Kansas, USA.
Daniel J ShapiroDivision of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Susan C LipsettDivision of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Adam L HershDivision of Pediatric Infectious Diseases, Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Samir S ShahDivision of Hospital Medicine, Cincinnati Children's Hospital Medicine Center, Cincinnati, Ohio, USA.
Thomas V BroganDivision of Critical Care, Seattle Children's Hospital, Seattle, Washington, USA.
Jeffrey S GerberDivision of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Derek J WilliamsDivision of Hospital Medicine, Department of Pediatrics, Monroe Carell Jr Children's Hospital at Vanderbilt, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Anne J BlaschkeDivision of Pediatric Infectious Diseases, Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Jonathan D CogenDivision of Pulmonary Medicine and Sleep Medicine, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.
Mark I NeumanDivision of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.

Funding

Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
CTSA K12 Program at University of Colorado DenverK12TR004412 · NCATS · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM · 2024 to 2026
$3.2M
Metabolomic Prediction of Pneumonia SeverityR21AI154239 · NIAID · UNIVERSITY OF COLORADO DENVER · PI AMBROGGIO, LILLIAM · 2021 to 2022
$428k
AHRQ HHS T32 HS000063NCATS NIH HHS K12 TR004412NCATS NIH HHS UM1 TR004399NIAID NIH HHS R21 AI154239
6 · The paper itself

Abstract

backgroundIncomplete uptake of guidelines can lead to nonstandardized care, increased expenditures, and adverse clinical outcomes. The objective of this study was to evaluate the impact of the 2011 Pediatric Infectious Diseases Society and Infectious Diseases Society of America (PIDS/IDSA) pediatric community-acquired pneumonia (CAP) guideline that emphasized aminopenicillin use and de-emphasized the use of chest radiographs (CXRs) in certain populations.

methodsThis quasi-experimental study queried a national administrative database of children's hospitals to identify children aged 3 months-18 years with CAP who visited 1 of 28 participating hospitals from 2009 to 2021. PIDS/IDSA pediatric CAP guideline recommendations regarding antibiotic therapy, diagnostic testing, and imaging were evaluated. Segmented regression interrupted time series was used to measure guideline-concordant practices with interruptions for guideline publication and the Coronavirus Disease 2019 (COVID-19) pandemic.

resultsOf 315 384 children with CAP, 71 804 (22.8%) were hospitalized. Among hospitalized children, there was a decrease in blood culture performance (0.5% per quarter) and increase in aminopenicillin prescribing (1.1% per quarter). Among children discharged from the emergency department (ED), there was an increase in aminopenicillin prescription (0.45% per quarter), whereas the rate of obtaining CXRs declined (0.12% per quarter). However, use of CXRs rebounded during the COVID-19 pandemic (increase of 1.56% per quarter). Hospital length of stay, ED revisit rates, and hospital readmission rates remained stable.

conclusionsGuideline publication was associated with an increase of aminopenicillin prescribing. However, rates of diagnostic testing did not materially change, suggesting the need to consider implementation strategies to meaningfully change clinical practice for children with CAP.

Indexed as

Communicable DiseasesCommunity-Acquired InfectionsCOVID-19PneumoniaAnti-Bacterial AgentsChildEmergency Service, HospitalGuideline AdherenceHumansPandemicsPenicillinsRetrospective StudiesAnti-Bacterial AgentsPenicillinsantibioticsdiagnostic testingpediatricpneumonia

Identifiers

PMID37352841
PMCPMC11487097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.