Evidence map›Paper›PMID 37352733›Full record

ArticleDrug and alcohol dependence2023

Respondent-driven sampling is more efficient than facility-based strategies at identifying undiagnosed people who inject drugs living with HIV in India.

Allison M McFall, Sunil S Solomon, Bryan Lau, Carl Latkin, Aylur K Srikrishnan, Santhanam Anand, Canjeevaram K Vasudevan, Muniratnam Suresh Kumar, Gregory M Lucas, Shruti H Mehta

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Allison M McFallJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD, United States. Electronic address: amcfall2@jhu.edu.
Sunil S SolomonJohns Hopkins University School of Medicine, Infectious Diseases Department, Baltimore, MD, United States.
Bryan LauJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD, United States.
Carl LatkinJohns Hopkins Bloomberg School of Public Health, Department of Health, Behavior, and Society, Baltimore, MD, United States.
Aylur K SrikrishnanYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Santhanam AnandYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Canjeevaram K VasudevanYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Muniratnam Suresh KumarYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Gregory M LucasJohns Hopkins University School of Medicine, Infectious Diseases Department, Baltimore, MD, United States.
Shruti H MehtaJohns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD, United States.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Strategies to improve the HIV care continuum among key populations in IndiaR01DA041034 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2015 to 2021
$6.7M
Integrated Care Clinics for IDUs in India: a cluster randomized trialR01DA032059 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2011 to 2015
$6.3M
Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
PWID Opportunities to Improve TrEat and Retain (POINTER)R01DA049301 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2020 to 2025
$4.8M
Treatment outcomes and comorbidity in HIV-infected IDUK24DA035684 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M · 2014 to 2024
$1.5M
Investigating the Potential of Respondent-Driven Sampling to Reach Undiagnosed, Out-of-Care HIV-infected People Who Inject DrugsF31DA044046 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MCFALL, ALLISON MARIE · 2017 to 2018
$78k
NIAID NIH HHS P30 AI094189NIAID NIH HHS T32 AI102623NIDA NIH HHS F31 DA044046NIDA NIH HHS K24 DA035684NIDA NIH HHS R01 DA032059NIDA NIH HHS R01 DA041034NIDA NIH HHS R01 DA049301
6 · The paper itself

Abstract

introductionInjection drug use drives HIV epidemics in many low-resource settings, yet many people who inject drugs (PWID) living with HIV are not diagnosed. We assessed the ability of respondent-driven sampling (RDS) - which uses peer network connections - to identify undiagnosed PWID living with HIV compared to a facility-based strategy in India.

methodsIn six Indian cities from 2014 to 2017, integrated care centers (ICCs) provided HIV testing. From 2016 to 2017, RDS samples of PWID in these same cities were conducted. Using biometric matching, characteristics associated with identification by RDS only and both RDS and ICC, compared to ICC only were explored. Undiagnosed individuals tested positive and did not report a prior diagnosis. The number needed to recruit (NNR) (average number recruited to find one undiagnosed PWID living with HIV) and the identification rate (average number undiagnosed PWID identified per week) assessed the efficiency of RDS vs. ICCs.

resultsThere were 10,759 ICC clients and 6012 RDS participants; 40% of RDS participants were also ICC clients resulting in 14,397 unduplicated PWID. PWID identified by RDS vs. ICC only were more likely to be male (adjusted odds ratios [aOR] RDS only: 6.8, both: 2.7) and living with HIV but undiagnosed (aOR RDS only: 2.5, both: 1.5). Overall, the RDS NNR was 11 and the ICC NNR was 26. The RDS identification rate (18.6/week) was faster than the ICC identification rate (2.7/week) overall and in all cities.

conclusionsRDS required screening fewer PWID and more rapidly identified undiagnosed PWID living with HIV as compared to ICCs.

Indexed as

Drug UsersHIV InfectionsSubstance Abuse, IntravenousFemaleHumansIndiaMalePrevalenceSurveys and QuestionnairesHIV testingIndiaPeople who inject drugsRespondent-driven sampling

Identifiers

PMID37352733
PMCPMC10330670

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.