Evidence map›Paper›PMID 37352435›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2023

Ethnic Disparities in Early-Onset Gastric Cancer Persist across Rural-Urban Geographies.

Manasa Narasimman, Sandi L Pruitt, Caitlin C Murphy, Amit G Singal, Anna Tavakkoli

Open access · greenAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Cancer Burden in Persistent Poverty Areas across the Cancer Continuum: A Scoping Review to Identify Gaps and Opportunities for Future Research.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  2. Gastric Cancer Risk among Immigrants and Socioeconomic Groups in the Netherlands.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Manasa NarasimmanDepartment of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0001-6838-8054
Sandi L PruittPeter O'Donnell Jr. School of Public Health, The University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0002-1007-9176
Caitlin C MurphySchool of Public Health, University of Texas Health Science Center at Houston, Houston, Texas.ORCID 0000-0001-9365-0691
Amit G SingalDepartment of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0002-1172-3971
Anna TavakkoliDepartment of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0001-9921-9085
Southwestern Medical Center · USThe University of Texas Health Science Center at Houston · USThe University of Texas Southwestern Medical Center · US

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7M
Evaluation of Multi-level factors Associated with post-ERCP OutcomesK23DK132409 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Anna Tavakkoli · 2023 to 2026
$638k
NCI NIH HHS P30 CA142543NIDDK NIH HHS K23 DK132409University of Texas Southwestern Medical Center (UTSW) IRG-17-174-13University of Texas Southwestern Medical Center (UTSW) P30CA142543
6 · The paper itself

Abstract

backgroundThe incidence of noncardia gastric cancer is increasing in adults ages less than 50 years old. Early-onset gastric cancer (EOGC) is characterized by ethnic disparities occurring more in Hispanic persons than non-Hispanic persons. It is unknown whether rural-urban disparities exist in EOGC and if this intersects with ethnic disparities.

methodsWe utilized the Surveillance Epidemiology and End Results 17 Census Tract-level Socioeconomic Status and Rurality Database from 2006 to 2018 to calculate incidence rates and incidence rate ratios of EOGC among Hispanic and non-Hispanic persons by census tract rural-urban location, age, gender, persistent poverty, and stage of disease. We used the Tiwari Method to estimate incidence rate ratios with 95% confidence intervals (CI).

resultsHispanic persons had higher incidence rates of EOGC compared with non-Hispanic persons in both rural [incident rate ratios (IRR), 2.12; 95% confidence interval (CI), 1.64-2.73] and urban census tracts (IRR, 2.03; 95% CI, 1.91-2.16). Similar findings were seen when comparing Hispanic to non-Hispanic persons in rural and urban census tracts by age, stage of disease, and persistent poverty.

conclusionsHigher incidence rates of EOGC among Hispanic persons persist across rural-urban locations. Further research is needed to understand the etiology of this elevated risk in young Hispanics and interventions that may help to modify their outcome. IMPACT: While other cancers have ethnic disparities which may differ by rural-urban location, the ethnic disparity in EOGC among Hispanic and non-Hispanic persons does not differ by rural-urban residence.

Identifiers

PMID37352435
PMCPMC12483174
OpenAlexW4381839117

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.