Evidence map›Paper›PMID 37352353›Full record

ArticleScience advances2023

IPAC integrates rewarding and environmental memory during the acquisition of morphine CPP.

Huan-Min Liu, Ming-Lu Liao, Guan-Xi Liu, Lai-Jian Wang, Dian Lian, Jie Ren, Xin-Tian Chi, Zhuo-Ran Lv, Meng Liu, Yan Wu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. GPe Projections to the Retrorubral Field Give Rise to Diverging GABAergic and DAergic Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Huan-Min LiuThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0000-0002-0404-2895
Ming-Lu LiaoThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0009-0000-7854-3134
Guan-Xi LiuThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0000-0001-8891-9588
Lai-Jian WangGuangdong Province Key Laboratory of Brain Function and Disease, Zhongshan Medical School, Sun Yat-sen University, 74 Zhongshan Road 2, Guangzhou 510080, China.ORCID 0000-0002-6513-1859
Dian LianThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0000-0002-1226-3233
Jie RenThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0000-0002-3061-4068
Xin-Tian ChiThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0009-0004-3551-7090
Zhuo-Ran LvThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.
Meng LiuDepartment of Anesthesia and Pain Medicine, Guangzhou First People's Hospital, Guangzhou 510000, China.ORCID 0009-0005-2686-7571
Yan WuDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0002-8920-2340
Ting XuGuangdong Province Key Laboratory of Brain Function and Disease, Zhongshan Medical School, Sun Yat-sen University, 74 Zhongshan Road 2, Guangzhou 510080, China.ORCID 0000-0001-6123-9814
Jia-You WeiNeuroscience Program, Zhongshan School of Medicine, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China.ORCID 0000-0001-9412-1951
Xia FengDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0001-8182-9803
Bin JiangGuangdong Province Key Laboratory of Brain Function and Disease, Zhongshan Medical School, Sun Yat-sen University, 74 Zhongshan Road 2, Guangzhou 510080, China.ORCID 0000-0002-8229-2160
Xue-Qin ZhangThe Institute of Mental Psychology, School of Health Management, The Affiliated Brain Hospital (Guangzhou Huiai Hospital), Guangzhou Medical University, Guangzhou 510370, China.ORCID 0000-0003-1917-6228
Wen-Jun XinGuangdong Province Key Laboratory of Brain Function and Disease, Zhongshan Medical School, Sun Yat-sen University, 74 Zhongshan Road 2, Guangzhou 510080, China.ORCID 0000-0002-5380-8738
Guangzhou Psychiatric Hospital · CNSun Yat-sen University · CNGuangzhou First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between rewarding and drug-related memory is a leading factor for the formation of addiction, yet the neural circuits underlying the association remain unclear. Here, we showed that the interstitial nucleus of the posterior limb of the anterior commissure (IPAC) integrated rewarding and environmental memory information by two different receiving projections from ventral tegmental area (VTA) and nucleus accumbens shell region (NAcSh) to mediate the acquisition of morphine conditioned place preference (CPP). A projection from the VTA GABAergic neurons (VTA

Indexed as

MorphineVentral Tegmental AreaGABAergic Neuronsgamma-Aminobutyric AcidRewardgamma-Aminobutyric AcidMorphine

Identifiers

PMID37352353
PMCPMC10289658
OpenAlexW4381801976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.