Evidence map›Paper›PMID 37352351›Full record

ArticleScience advances2023

A missense mutation in

Mingle Dou, Ming Li, Zhuqing Zheng, Qiuming Chen, Yongji Wu, Jinxin Wang, Huiquan Shan, Fei Wang, Xuelei Dai, Yunjia Li and 15 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. TheAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
  4. Functional Mutations in theVeterinary sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 4 countries.

Mingle DouKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0003-2590-0649
Ming LiKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0001-7049-8666
Zhuqing ZhengKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0002-4570-7646
Qiuming ChenKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0002-2334-176X
Yongji WuCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shannxi, 712100, China.
Jinxin WangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.
Huiquan ShanKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.
Fei WangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.
Xuelei DaiKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0002-7681-7338
Yunjia LiKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.
Zhirui YangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.
Guanghui TanKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0001-6465-8715
Funong LuoKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.
Lei ChenSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, Shaanxi, 710072, China.
Yun Stone ShiState Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Medical School, Nanjing University, Nanjing, Jiangsu, 210032, China.ORCID 0000-0002-8842-9818
Jiang Wei WuKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0009-0005-6103-2115
Xiong-Jian LuoCenter for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan, 650204, China.ORCID 0000-0003-2543-8845
Hojjat Asadollahpour NanaeiKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0002-5220-828X
Zhannur NiyazbekovaKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0002-8556-0212
Guojie ZhangCentre for Evolutionary and Organismal Biology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310000, China.ORCID 0000-0001-6860-1521
Wen WangSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, Shaanxi, 710072, China.ORCID 0000-0002-7801-2066
Shanting ZhaoCollege of Veterinary Medicine, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0003-2619-4467
Wenxin ZhengXinjiang Academy of Animal Sciences, Urumqi, Xinjiang, 830011, China.ORCID 0000-0002-6525-2212
Xihong WangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0002-8277-969X
Yu JiangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shannxi, 712100, China.ORCID 0000-0003-4821-3585
Agriculture and Forestry University · NPNorth West Agriculture and Forestry University · CNNorthwestern Polytechnical University · CNHuazhong Agricultural University · CNKunming Institute of Zoology · CNModel Animal Research Center · CNUniversity of Konstanz · DEXinjiang Academy of Animal Science · CNXinjiang Agricultural University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increased tameness to reduce avoidance of human in wild animals has been long proposed as the key step of animal domestication. The tameness is a complex behavior trait and largely determined by genetic factors. However, the underlying genetic mutations remain vague and how they influence the animal behaviors is yet to be explored. Behavior tests of a wild-domestic hybrid goat population indicate the locus under strongest artificial selection during domestication may exert a huge effect on the flight distance. Within this locus, only one missense mutation

Indexed as

Animals, DomesticBehavior, AnimalDomesticationMutation, MissenseRibonucleoside Diphosphate ReductaseAnimalsGoatsMiceSelection, GeneticRibonucleoside Diphosphate Reductase

Identifiers

PMID37352351
PMCPMC10289655
OpenAlexW4381804400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.