Evidence map›Paper›PMID 37352280›Full record

ArticlePloS one2023

Epidemiology of SARS-CoV-2 transmission and superspreading in Salt Lake County, Utah, March-May 2020.

Joseph Walker, Tiffany Tran, Brooke Lappe, Paul Gastanaduy, Prabasaj Paul, Ian T Kracalik, Victoria L Fields, Adriana Lopez, Amy Schwartz, Nathaniel M Lewis and 10 more

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Joseph WalkerCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Tiffany TranCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Brooke LappeCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Paul GastanaduyCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Prabasaj PaulCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Ian T KracalikCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Victoria L FieldsCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Adriana LopezCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Amy SchwartzCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.ORCID 0000-0001-8244-7225
Nathaniel M LewisCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Jacqueline E TateCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Hannah L KirkingCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Aron J HallCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Eric PevznerCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Ha KhongSalt Lake County Health Department, Salt Lake City, Utah, United States of America.
Maureen SmitheeSalt Lake County Health Department, Salt Lake City, Utah, United States of America.
Jason LowrySalt Lake County Health Department, Salt Lake City, Utah, United States of America.
Angela DunnUtah Department of Health, Salt Lake City, Utah, United States of America.
Tair KiphibaneSalt Lake County Health Department, Salt Lake City, Utah, United States of America.
Cuc H TranCOVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.ORCID 0000-0003-4798-8039

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding the drivers of SARS-CoV-2 transmission can inform the development of interventions. We evaluated transmission identified by contact tracing investigations between March-May 2020 in Salt Lake County, Utah, to quantify the impact of this intervention and identify risk factors for transmission.

methodsRT-PCR positive and untested symptomatic contacts were classified as confirmed and probable secondary case-patients, respectively. We compared the number of case-patients and close contacts generated by different groups, and used logistic regression to evaluate factors associated with transmission.

resultsData were collected on 184 index case-patients and up to six generations of contacts. Of 1,499 close contacts, 374 (25%) were classified as secondary case-patients. Decreased transmission odds were observed for contacts aged <18 years (OR = 0.55 [95% CI: 0.38-0.79]), versus 18-44 years, and for workplace (OR = 0.36 [95% CI: 0.23-0.55]) and social (OR = 0.44 [95% CI: 0.28-0.66]) contacts, versus household contacts. Higher transmission odds were observed for case-patient's spouses than other household contacts (OR = 2.25 [95% CI: 1.52-3.35]). Compared to index case-patients identified in the community, secondary case-patients identified through contract-tracing generated significantly fewer close contacts and secondary case-patients of their own. Transmission was heterogeneous, with 41% of index case-patients generating 81% of directly-linked secondary case-patients.

conclusionsGiven sufficient resources and complementary public health measures, contact tracing can contain known chains of SARS-CoV-2 transmission. Transmission is associated with age and exposure setting, and can be highly variable, with a few infections generating a disproportionately high share of onward transmission.

Indexed as

COVID-19SARS-CoV-2Contact TracingHumansRisk FactorsUtah

Identifiers

PMID37352280
PMCPMC10289415

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.