Evidence map›Paper›PMID 37352172›Full record

ArticlePloS one2023

Deep-Fuzz: A synergistic integration of deep learning and fuzzy water flows for fine-grained nuclei segmentation in digital pathology.

Nirmal Das, Satadal Saha, Mita Nasipuri, Subhadip Basu, Tapabrata Chakraborti

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In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nirmal DasDeapartemnt of Computer Science and Engineering (AIML), Institute of Engineering and Management, Kolkata, West Bengal, India.ORCID 0000-0001-8980-2111
Satadal SahaDepartment of Electrical and Computer Engineering, MCKV Institute of Engineering, Howrah, West Bengal, India.
Mita NasipuriDeapartment of Computer Science and Engineering, Jadavpur University, Kolkata, West Bengal, India.
Subhadip BasuDeapartment of Computer Science and Engineering, Jadavpur University, Kolkata, West Bengal, India.
Tapabrata ChakrabortiUniversity College London and The Alan Turing Institute, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robust semantic segmentation of tumour micro-environment is one of the major open challenges in machine learning enabled computational pathology. Though deep learning based systems have made significant progress, their task agnostic data driven approach often lacks the contextual grounding necessary in biomedical applications. We present a novel fuzzy water flow scheme that takes the coarse segmentation output of a base deep learning framework to then provide a more fine-grained and instance level robust segmentation output. Our two stage synergistic segmentation method, Deep-Fuzz, works especially well for overlapping objects, and achieves state-of-the-art performance in four public cell nuclei segmentation datasets. We also show through visual examples how our final output is better aligned with pathological insights, and thus more clinically interpretable.

Indexed as

Deep LearningCell NucleusImage Processing, Computer-AssistedMachine LearningWaterWater

Identifiers

PMID37352172
PMCPMC10289330

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.