Evidence map›Paper›PMID 37351771›Full record

ReviewLa Radiologia medica2023

Pivotal role of multiphase computed tomography angiography for collateral assessment in patients with acute ischemic stroke.

Giorgio Busto, Andrea Morotti, Edoardo Carlesi, Alessandro Fiorenza, Francesca Di Pasquale, Sara Mancini, Ivano Lombardo, Elisa Scola, Davide Gadda, Marco Moretti and 2 more

Open access · hybridAbstract readReview
In one paragraph

Review in La Radiologia medica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The value of venous outflow assessment based on multiphase CTA in predicting the prognosis of endovascular therapy for acute ischemic stroke patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Multi-phase CT-Angiography outperforms angiographic careggi collateral score and predicts functional outcome in acute ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Giorgio BustoNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy. bustog@aou-careggi.toscana.it.ORCID http://orcid.org/0000-0002-7007-6030
Andrea MorottiNeurology Unit, Department of Neurological Sciences and Vision, ASST Spedali Civili, Brescia, Italy.
Edoardo CarlesiNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy.
Alessandro FiorenzaNeurology Unit, Department of Neurological Sciences and Vision, ASST Spedali Civili, Brescia, Italy.
Francesca Di PasqualeDiagnostic Imaging Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Sara ManciniNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy.
Ivano LombardoNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy.
Elisa ScolaNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy.
Davide GaddaNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy.
Marco MorettiNeuroradiology Unit, Department of Radiology, Careggi University Hospital, Florence, Italy.
Vittorio MieleDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Enrico FainardiNeuroradiology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Azienda Ospedaliero-Universitaria Careggi · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cerebral collateral circulation is the main compensatory mechanism that maintains the ischemic penumbra viable, the tissue at risk for infarction that can be saved if blood flow is restored by reperfusion therapies. In clinical practice, the extent of collateral vessels recruited after vessel occlusion can be easily assessed with computed tomography angiography (CTA) using two different techniques: single-phase CTA (sCTA) and multi-phase CTA (mCTA). Both these methodologies have demonstrated a high prognostic predictive value for prognosis due to the strong association between the presence of good collaterals and favorable radiological and clinical outcomes in patients with acute ischemic stroke (AIS). However, mCTA seems to be superior to sCTA in the evaluation of collaterals and a promising tool for identifying AIS patients who can benefit from reperfusion therapies. In particular, it has recently been proposed the use of mCTA eligibility criteria has been recently proposed for the selection of AIS patients suitable for endovascular treatment instead of the current accepted criteria based on CT perfusion. In this review, we analyzed the characteristics, advantages and disadvantages of sCTA and mCTA to better understand their fields of application and the potential of mCTA in becoming the method of choice to assess collateral extent in AIS patients.

Indexed as

Brain IschemiaIschemic StrokeStrokeCerebral AngiographyComputed Tomography AngiographyHumansRetrospective StudiesTomography, X-Ray ComputedAcute ischemic strokeCollateralsMultiphase CT angiographyReperfusion therapies

Identifiers

PMID37351771
PMCPMC10338577
OpenAlexW4381715468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.