Evidence map›Paper›PMID 37351342›Full record

ArticleFrontiers in genetics2023

A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and myopia.

Chen Jiang, Ronald B Melles, Jie Yin, Qiao Fan, Xiaobo Guo, Ching-Yu Cheng, Mingguang He, David A Mackey, Jeremy A Guggenheim, Caroline Klaver and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. IMI-Myopia Genetics Report.Investigative ophthalmology & visual science · 2025
    Review
  9. Revisiting the Trans-Ancestry Genetic Correlation of Refractive Error.Investigative ophthalmology & visual science · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 6 countries.

Chen JiangDivision of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, United States.
Ronald B MellesKPNC, Department of Ophthalmology, Redwood City, CA, United States.
Jie YinDivision of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, United States.
Qiao FanCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Xiaobo GuoDepartment of Statistical Science, School of Mathematics, Sun Yat-Sen University, Guangzhou, China.
Ching-Yu ChengOcular Epidemiology Research Group, Singapore Eye Research Institute, Singapore, Singapore.
Mingguang HeState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China.
David A MackeyLions Eye Institute, Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, WA, Australia.
Jeremy A GuggenheimSchool of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom.
Caroline KlaverDepartment Ophthalmology, Department Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands.
Consortium for Refractive Error and Myopia (CREAM)
K Saidas NairDepartment of Ophthalmology and Department of Anatomy, School of Medicine, University of California, San Francisco, CA, United States.
Eric JorgensonRegeneron Genetics Center, Tarrytown, NY, United States.
Hélène ChoquetDivision of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, United States.
Kaiser Permanente · USCardiff University · GBCentre for Eye Research Australia · AUDuke-NUS Medical School · SGErasmus MC · NLLions Eye Institute · AURegeneron (United States) · USSingapore Eye Research Institute · SGSun Yat-sen University · CNUniversity of California, San Francisco · US

Funding

A Resource for Genetic Epidemiology Research in Adult Health and AgingRC2AG036607 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI RISCH, NEIL J., SCHAEFER, CATHERINE ANN · 2009 to 2010
$24.8M
Determining Molecular and Cellular Mechanisms of GlaucomaR01EY022891 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAIR, KAYARAT SAIDAS · 2013 to 2017
$2.0M
Characterizing the Molecular Mechanisms of PRSS56-Dependent Ocular Growth and Refractive ErrorR01EY032666 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAIR, KAYARAT SAIDAS · 2022 to 2025
$1.7M
Diversity Supplement_TorresR01EY033015 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAIR, KAYARAT SAIDAS · 2022 to 2025
$1.6M
The Role of Refractive Error in the Etiology of GlaucomaR01EY027004 · NEI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHOQUET, HELENE · 2017 to 2020
$1.6M
NEI NIH HHS R01 EY022891NEI NIH HHS R01 EY027004NEI NIH HHS R01 EY032666NEI NIH HHS R01 EY033015NIA NIH HHS RC2 AG036607
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

axial lengtheye biometrygeneticsGWASmyopiarefractive errorssingle nucleotide polymorphisms (SNPs)

Identifiers

PMID37351342
PMCPMC10282939
OpenAlexW4379796286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.