Evidence map›Paper›PMID 37351330›Full record

ArticleAPL bioengineering2023

4D Light-sheet imaging and interactive analysis of cardiac contractility in zebrafish larvae.

Xinyuan Zhang, Milad Almasian, Sohail S Hassan, Rosemary Jotheesh, Vinay A Kadam, Austin R Polk, Alireza Saberigarakani, Aayan Rahat, Jie Yuan, Juhyun Lee and 2 more

Abstract read
In one paragraph

Article in APL bioengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Emerging Light-Sheet Fluorescence Microscopy for Cardiac Vascular Imaging in Zebrafish.Current treatment options in cardiovascular medicine · 2026
    Review
  2. Article
  3. Light-Sheet Imaging to Reveal Cardiac Structure in Rodent Hearts.Journal of visualized experiments : JoVE · 2024
    Article
  4. 4D Light-sheet Imaging of Zebrafish Cardiac Contraction.Journal of visualized experiments : JoVE · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xinyuan ZhangDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0009-0008-1914-3024
Milad AlmasianDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0009-0001-4159-8825
Sohail S HassanDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0000-0001-5340-2503
Rosemary JotheeshDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0009-0001-2585-7532
Vinay A KadamDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0000-0003-3303-7523
Austin R PolkDepartment of Computer Science, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0009-0003-1279-766X
Alireza SaberigarakaniDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0009-0008-7748-0424
Aayan RahatDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0009-0005-7616-8664
Jie YuanDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas 75080, USA.ORCID https://orcid.org/0000-0002-7789-6744
Juhyun LeeDepartment of Bioengineering, The University of Texas at Arlington, Arlington, Texas 76019, USA.ORCID https://orcid.org/0000-0002-9609-4376
Kelli CarrollDepartment of Biology, Austin College, Sherman, Texas 75090, USA.ORCID https://orcid.org/0000-0001-6120-8321

Funding

High spatiotemporal optical imaging to study dynamics of 3D cell motion and behavior in living organismsR35GM150947 · NIGMS · UNIVERSITY OF TEXAS ARLINGTON · PI Juhyun Lee · 2023 to 2026
$1.5M
Volumetric imaging and computation to characterize cardiac electromechanical couplingR01HL162635 · NHLBI · UNIVERSITY OF TEXAS DALLAS · PI Yichen Ding · 2023 to 2026
$1.5M
Integrating imaging and computation to characterize neural crest cells in the myocardial development and regenerationR00HL148493 · NHLBI · UNIVERSITY OF TEXAS DALLAS · PI DING, YICHEN · 2020 to 2022
$730k
NHLBI NIH HHS R00 HL148493NHLBI NIH HHS R01 HL162635NIGMS NIH HHS R35 GM150947
6 · The paper itself

Abstract

Despite ongoing efforts in cardiovascular research, the acquisition of high-resolution and high-speed images for the purpose of assessing cardiac contraction remains challenging. Light-sheet fluorescence microscopy (LSFM) offers superior spatiotemporal resolution and minimal photodamage, providing an indispensable opportunity for the

Identifiers

PMID37351330
PMCPMC10283270

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.