ArticleFrontiers in psychiatry2023
Predicting depressive symptom by cardiometabolic indicators in mid-aged and older adults in China: a population-based cross-sectional study.
Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between the triglyceride glucose index and depression: a meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Relationship between triglyceride glucose-waist circumference and depressive symptoms in Chinese older adults: The China health and retirement longitudinal study.Brain, behavior, & immunity - health · 2026Article
- Triglyceride-glucose index, genetic predisposition, and incident depression: a prospective cohort study from the UK Biobank.Psychological medicine · 2026Article
- Sugar-sweetened beverage consumption, waist-to-height ratio and psychological symptoms among Chinese adolescents.Scientific reports · 2026Article
- Multidimensional neuropsychological heterogeneity in obstructive sleep apnea: deep clinical phenotyping in a single-center cohort, population proteomic context, and depressive-burden risk stratification.Frontiers in immunology · 2026Article
- Abdominal Obesity Indices as Predictors of Psychiatric Morbidity in a Large-Scale Taiwanese Cohort.Nutrients · 2025Article
- Body roundness index and mental health in middle-aged and elderly adults: a prospective cohort study.Scientific reports · 2025Article
- Analysis of the nonlinear relationships between insulin resistance indicators such as LAP and TyG and depression, and population characteristics: a cross-sectional study.European journal of medical research · 2025Article
- Association between triglyceride-glucose (TyG) index and risk of depression in middle-aged and elderly Chinese adults: Evidence from a large national cohort study.Biomolecules & biomedicine · 2025Article
- The relationship between VAI, LAP, and depression and the mediation role of sleep duration-evidence from NHANES 2005-2020.BMC psychiatry · 2025Article
- A significant atypical U-shaped relationship exists between Lipid Accumulation Product and depression prevalence among Chinese middle-aged and elderly men: a cross-sectional study based on CHARLS.Frontiers in nutrition · 2025Article
- The association of triglyceride glucose waist-to-height ratio index with depression in United States adults.Frontiers in nutrition · 2025Article
- Association between the triglyceride glucose-waist circumference index and cardiovascular disease across different glycemic statuses among middle-aged and older Chinese adults.Frontiers in cardiovascular medicine · 2025Article
- Elevated body roundness index increases the risk of cardiovascular disease in Chinese patients with circadian syndrome.Frontiers in endocrinology · 2025Article
- Association between triglyceride-glucose index and its combination with obesity indicators and depression: findings from NHANES 2005-2020.Frontiers in psychiatry · 2025Article
- L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.Frontiers in public health · 2025Article
- The nonlinear relationship between triglyceride glucose-waist circumference and stroke risk in middle-aged and elderly people: a nationwide prospective cohort study of the CHARLS.Lipids in health and disease · 2024Observational
- Atherogenic Index of Plasma as a Mediator in the association between Body Roundness Index and Depression: insights from NHANES 2005-2018.Lipids in health and disease · 2024Article
- The relationship between depression and lipid accumulation product: a population-based study.Frontiers in psychiatry · 2024Article
- Integration of Immunometabolic Composite Indices and Machine Learning for Diabetic Retinopathy Risk Stratification: Insights from NHANES 2011 - 2020.Ophthalmology scienceArticle
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20 authors.
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Abstract
Objective: Depressive symptom is a serious mental illness often accompanied by physical and emotional problems. The prevalence of depressive symptom in older adults has become an increasingly important public health priority. Our study used cardiometabolic indicators to predict depressive symptom in middle-aged and older adults in China. Methods: The data came from the China Health and Retirement Longitudinal Study 2011 (CHARLS2011), which was a cross-sectional study. The analytic sample included 8,942 participants aged 45 years or above. The study evaluated the relationship between cardiometabolic indicators and depression by measuring 13 indicators, including body mass index (BMI), waist circumference, waist-height ratio (WHtR), conicity index, visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), a body shape index (ABSI), body roundness index (BRI), triglyceride glucose index (TyG-index) and its correlation index (TyG-BMI, TyG-waist circumference, TyG-WHtR). Binary logistic regression analysis was used to examine the association between thirteen cardiometabolic indicators and depressive symptom. In addition, the receiver operating characteristic (ROC) curve analysis and area under curve (AUC) were used to evaluate the predictive anthropometric index and to determine the optimum cut-off value. Results: The study included 8,942 participants, of whom 4,146 (46.37%) and 4,796 (53.63%) were male and female. The prevalence of depressive symptom in mid-aged and older adults in China was 41.12% in males and 55.05% in females. The results revealed that BMI [AUC = 0.440, 95%CI: 0.422-0.457], waist circumference [AUC = 0.443, 95%CI: 0.425-0.460], WHtR [AUC = 0.459, 95%CI: 0.441-0.476], LAP [AUC = 0.455, 95%CI: 0.437-0.472], BRI [AUC = 0.459, 95%CI: 0.441-0.476], CVAI [AUC = 0.449, 95%CI: 0.432-0.467], TyG-BMI [AUC = 0.447, 95%CI: 0.429-0.465], and TyG-waist circumference [AUC =0.452, 95%CI: 0.434-0.470] were weak predictors of depressive symptom ( Conclusion: Most cardiometabolic indicators have important value in predicting depressive symptom. Our results can provide measures for the early identification of depressive symptom in middle-aged and older adults in China to reduce the prevalence of depressive symptom and improve health.
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