ArticleFrontiers in oncology2023
Colorectal cancer in patients of advanced age is associated with increased incidence of
Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Anemia-Related Red Flags as Distinctive Early Indicators for Colorectal Cancer Diagnosis in Older Adults.Journal of clinical medicine · 2026Article
- Age and Colorectal Cancer Outcomes: A Comparative Analysis Between Patients Younger and Older than 70 Years.Current oncology (Toronto, Ont.) · 2026Article
- Clinicopathological Features of Right vs. Left Colorectal Carcinomas: Do the Differences Really Matter?Life (Basel, Switzerland) · 2026Article
- Molecular Mechanisms Driving Metastatic Progression Within the Aged Tumor Microenvironment.International journal of molecular sciences · 2025Review
- Advances in Hereditary Colorectal Cancer: How Precision Medicine Is Changing the Game.Cancers · 2025Review
- Management of Elderly Colorectal Cancer Patients: A Comprehensive Review Encompassing Geriatric Assessment.Cancers · 2025Review
- Real-world characteristics and outcomes of patients with BRAFESMO real world data and digital oncology · 2025Article
- The Relevance of Sex and Age as Non-Modifiable Risk Factors in Relation to Clinical-Pathological Parameters in Colorectal Cancer.Life (Basel, Switzerland) · 2025Article
- Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The highest incidence of colorectal cancer (CRC) is in patients diagnosed at 80 years or older highlighting a need for understanding the clinical and molecular features of these tumors. Methods. In this retrospective cohort study, 544 CRCs underwent next generation sequencing and mismatch repair (MMR) evaluation. Molecular and clinical features were compared between 251 patients with traditional-onset CRC (50-69 years at diagnosis) and 60 with late-onset CRC (>80 years at diagnosis). Results: Late-onset CRC showed a significantly higher rate of right-sided tumors (82% vs 35%), MMR deficiency (35% vs. 8%) and Discussion: In summary, there was a higher rate of dMMR and
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