Evidence map›Paper›PMID 37350916›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2023

A Query Engine for Self-controlled Case Series, with an application to COVID-19 EHR data.

Xiaojin Li, Yan Huang, Licong Cui, Guo-Qiang Zhang

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Quantitatively assessing the impact of the quality of SNOMED CT subtype hierarchy on cohort queries.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  2. VisualSphere: a Web-based Interactive Visualization System for Clinical Research Data.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaojin LiMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.
Yan HuangMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.
Licong CuiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX.
Guo-Qiang ZhangMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.

Funding

SCH: Neurophysiological AI-Ready Data ResourceR01NS126690 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHANG, GUO-QIANG · 2022 to 2025
$1.2M
Biomedical Terminology Quality Assurance for Enhancing Clinical Queries over Electronic Health RecordsR01LM013335 · NLM · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CUI, LICONG · 2020 to 2021
$663k
NINDS NIH HHS R01 NS126690NLM NIH HHS R01 LM013335
6 · The paper itself

Abstract

Self-controlled case series (SCCS) is a statistical method in epidemiological study design that uses individuals as their own controls, with comparisons made within the same individuals at different time points of observation. SCCS has been applied in settings where it is difficult to identify comparison or control groups. To provide computational support for SCCS, we introduce a query engine called Self-Controlled Case Query (SCCQ) and use it to extract cohorts of self-controlled case series from a large-scale COVID-19 Electronic Health Records (EHR) dataset. Visual summary of the queried population through the R-Shiny visualization framework offers SCCQ's query result dashboard to the researcher. SCCQ allows the export of query-generated raw data files with a portable format that researchers can extend to create more intricate and robust visualization capabilities without needing a high-level of technical or statistical background. Our validation and evaluation experiments uncovered COVID-19 outcomes to be consistent with existing research findings. With SCCQ, cohort exploration, data extraction, and information visualization can be provided for structured EHR data to lower the barrier for clinical and epidemiological research.

Identifiers

PMID37350916
PMCPMC10283100

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.