Evidence map›Paper›PMID 37350870›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2023

Linking Ambient NO2 Pollution Measures with Electronic Health Record Data to Study Asthma Exacerbations.

Alana Schreibman, Sherrie Xie, Rebecca A Hubbard, Blanca E Himes

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alana SchreibmanDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.
Sherrie XieDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.
Rebecca A HubbardDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.
Blanca E HimesDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
CEBPD-Mediated Mechanisms of Glucocorticoid Insensitivity in Severe AsthmaR01HL133433 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HIMES, BLANCA E · 2017 to 2021
$3.2M
Precision Approaches to Reduce Asthma Disparities with Electronic Health Record DataR01HL162354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HUBBARD, REBECCA, WEISSMAN, GARY · 2022 to 2025
$3.1M
Steer and trees summer research programsR25ES021649 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI FIELD, JEFFREY M · 2013 to 2022
$830k
NHLBI NIH HHS R01 HL133433NHLBI NIH HHS R01 HL162354NIEHS NIH HHS P30 ES013508NIEHS NIH HHS R25 ES021649
6 · The paper itself

Abstract

Electronic health record (EHR)-derived data can be linked to geospatially distributed socioeconomic and environmental factors to conduct large-scale epidemiologic studies. Ambient NO2 is a known environmental risk factor for asthma. However, health exposure studies often rely on data from geographically sparse regulatory monitors that may not reflect true individual exposure. We contrasted use of interpolated NO2 regulatory monitor data with raw satellite measurements and satellite-derived ground estimates, building on previous work which has computed improved exposure estimates from remotely sensed data. Raw satellite and satellite-derived ground measurements captured spatial variation missed by interpolated ground monitor measurements. Multivariable analyses comparing these three NO2 measurement approaches (interpolated monitor, raw satellite, and satellite-derived) revealed a positive relationship between exposure and asthma exacerbations for both satellite measurements. Exposure-outcome relationships using the interpolated monitor NO2 were inconsistent with known relationships to asthma, suggesting that interpolated monitor data might yield misleading results in small region studies.

Identifiers

PMID37350870
PMCPMC10283087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.