Evidence map›Paper›PMID 37350793›Full record

ArticleNeurotrauma reports2023

Effect of Impact Parameters on a Unilateral Contusion Model of Spinal Cord Injury in a Virtual Population of Non-Human Primates.

Numaira Obaid, Ana-Maria Bojic, Shervin Jannesar, Ernesto Salegio, Yvette Nout-Lomas, Michael Beattie, Jacqueline Bresnahan, Carolyn Sparrey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotrauma reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Numaira ObaidMechatronic Systems Engineering, Simon Fraser University, Surrey, British Columbia, Canada.
Ana-Maria BojicBiomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada.
Shervin JannesarSchool of Engineering Science, Simon Fraser University, Burnaby, British Columbia, Canada.
Ernesto SalegioUniversity of California, Davis, California, USA.
Yvette Nout-LomasDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Michael BeattieBrain and Spinal Injury Center, Department of Neurological Surgery, University of California, San Francisco, California, USA.
Jacqueline BresnahanBrain and Spinal Injury Center, Department of Neurological Surgery, University of California, San Francisco, California, USA.
Carolyn SparreyMechatronic Systems Engineering, Simon Fraser University, Surrey, British Columbia, Canada.
Simon Fraser University · CAColorado State University · USInternational Collaboration On Repair Discoveries · CAUniversity of California, Davis · US

Funding

Embryonic stem cell therapy after cervical contusion SCI in NHPsR01NS105478 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BEATTIE, MICHAEL S, BRESNAHAN, JACQUELINE C · 2017 to 2021
$2.9M
NINDS NIH HHS R01 NS105478
6 · The paper itself

Abstract

Non-human primate (NHP) spinal cord injury experiments exhibit high intersubject variability in biomechanical parameters even when a consistent impact protocol is applied to each subject. Optimizing impact parameters to reduce this variability through experiments is logistically challenging in NHP studies. Finite element models provide a complimentary tool to inform experimental design without the cost and complexity of live animal studies. A morphologically variable virtual population (

Indexed as

animal modelscomputational modelscontusionspinal cord injuryvariability

Identifiers

PMID37350793
PMCPMC10282973
OpenAlexW4378976180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.