Evidence map›Paper›PMID 37350727›Full record

ArticleBalkan medical journal2023

Factors Influencing HIV Infection in Children Born to HIV-Infected Mothers in Turkey

Esra Zerdali, Bilgül Mete, Özlem Altuntaş Aydın, Alper Gündüz, İnci Yılmaz Nakir, Sibel Bolukçu, Hayat Kumbasar Karaosmanoğlu, Dilek Yıldız Sevgi, Meliha Meriç Koç, Fehmi Tabak

Open access · diamondAbstract read
In one paragraph

Article in Balkan medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Esra ZerdaliClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences Turkey, İstanbul Haseki Training and Research Hospital, İstanbul, TurkeyORCID 0000-0002-7023-6639
Bilgül MeteDepartment of Infectious Diseases and Clinical Microbiology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TurkeyORCID 0000-0001-9091-6087
Özlem Altuntaş AydınClinic of Infectious Diseases, University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, TurkeyORCID 0000-0001-8035-1385
Alper GündüzClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences Turkey, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyORCID 0000-0001-9154-844X
İnci Yılmaz NakirClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences Turkey, İstanbul Haseki Training and Research Hospital, İstanbul, TurkeyORCID 0000-0002-2987-1534
Sibel BolukçuClinic of Infectious Diseases and Clinical Microbiology, Bezmialem Vakıf University Hospital, İstanbul, TurkeyORCID 0000-0001-6475-3894
Hayat Kumbasar KaraosmanoğluClinic of Infectious Diseases, University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, TurkeyORCID 0000-0002-7716-3006
Dilek Yıldız SevgiClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences Turkey, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, TurkeyORCID 0000-0002-6047-4879
Meliha Meriç KoçClinic of Infectious Diseases and Clinical Microbiology, Bezmialem Vakıf University Hospital, İstanbul, TurkeyORCID 0000-0002-0563-6900
Fehmi TabakDepartment of Infectious Diseases and Clinical Microbiology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TurkeyORCID 0000-0001-8632-2825
Sağlık Bilimleri Üniversitesi · TRBezmiâlem Vakıf Üniversitesi · TRIstanbul University-Cerrahpaşa · TRHaseki Eğitim ve Araştırma Hastanesi · TRUniversity of Health Science · KH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Human immunodeficiency virus (HIV) is still a challenge for children. About 15 to 45% of the HIV positive pregnant women can transmit the virus to their children during pregnancy, delivery and/or breastfeeding. The risk of transmission can be decreased my several measures. Aims: To identify factors associated with HIV infection in children born to HIV-infected mothers. Study Design: A multi-center retrospective cohort study. Methods: A ten-year retrospective cohort study in five dedicated HIV centers was conducted. The 325 women in our cohort were between the ages of 18 and 45. During the study period, 44 (13.5%) of these women gave birth and 51 babies were born. Of the 51 infants, 7 (13.7%) were HIV/AIDS positive. Results: Among the factors studied, breastfeeding, having a HIV-positive sibling and being on antiretroviral treatment during pregnancy and detectable HIV-RNA during delivery were found statistically significant. A multivariable logistic regression analysis showed that being on antiretroviral treatment during pregnancy is the most important predictor of mother-to-child transmission. Conclusion: Mother-to-child transmission appears to be an important route of HIV transmission in Turkey. Lack of antiretroviral treatment during pregnancy appears to be a key factor in transmission.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousAdolescentAdultAnti-Retroviral AgentsFemaleHIVHumansInfectious Disease Transmission, VerticalMiddle AgedMothersPregnancyRetrospective StudiesTurkeyYoung AdultAnti-Retroviral Agents

Identifiers

PMID37350727
PMCPMC10500144
OpenAlexW4381715276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.