ArticleeLife2023
Targeted memory reactivation in human REM sleep elicits detectable reactivation.
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- The Role of Rapid Eye Movement Sleep in Neural Differentiation of Memories in the Hippocampus.Journal of cognitive neuroscience · 2026Article
- Manipulating memory processing during sleep to explore the critical duration of reactivation events.Neuropsychologia · 2025Article
- The Future of Non-Invasive Brain Stimulation in Sleep Medicine.Journal of sleep research · 2025Review
- Article
- Personalized targeted memory reactivation enhances consolidation of challenging memories via slow wave and spindle dynamics.NPJ science of learning · 2025Article
- Both slow wave and rapid eye movement sleep contribute to emotional memory consolidation.Communications biology · 2025Article
- Disarming emotional memories using targeted memory reactivation during rapid eye movement sleep.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- An update on recent advances in targeted memory reactivation during sleep.NPJ science of learning · 2024Review
- No Benefit in Memory Performance after Nocturnal Memory Reactivation Coupled with Theta-tACS.Clocks & sleep · 2024Article
- Auditory stimulation during REM sleep modulates REM electrophysiology and cognitive performance.Communications biology · 2024Article
- Cueing memory reactivation during NREM sleep engenders long-term plasticity in both brain and behaviour.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Item-specific neural representations during human sleep support long-term memory.PLoS biology · 2023Article
- Article
- Targeted memory reactivation elicits temporally compressed reactivation linked to spindles.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
It is now well established that memories can reactivate during non-rapid eye movement (non-REM) sleep, but the question of whether equivalent reactivation can be detected in rapid eye movement (REM) sleep is hotly debated. To examine this, we used a technique called targeted memory reactivation (TMR) in which sounds are paired with learned material in wake, and then re-presented in subsequent sleep, in this case REM, to trigger reactivation. We then used machine learning classifiers to identify reactivation of task-related motor imagery from wake in REM sleep. Interestingly, the strength of measured reactivation positively predicted overnight performance improvement. These findings provide the first evidence for memory reactivation in human REM sleep after TMR that is directly related to brain activity during wakeful task performance.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.