Evidence map›Paper›PMID 37350568›Full record

ArticleeLife2023

Mechanistic insights into robust cardiac I

Briana M Bohannon, Jessica J Jowais, Leif Nyberg, Vanessa Olivier-Meo, Valentina Corradi, D Peter Tieleman, Sara I Liin, H Peter Larsson

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  5. Beneficial action potential duration-shortening effects, but deleterious negative inotropism of IKs-activator docosahexaenoyl glycine in long QT syndrome type 2.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Briana M Bohannon *Department of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, United States.
Jessica J Jowais *Department of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, United States.
Leif NybergDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, United States.
Vanessa Olivier-MeoDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, United States.
Valentina CorradiDepartment of Biological Sciences and Centre for Molecular Simulation, University of Calgary, Calgary, Canada.
D Peter TielemanDepartment of Biological Sciences and Centre for Molecular Simulation, University of Calgary, Calgary, Canada.ORCID 0000-0001-5507-0688
Sara I LiinDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0001-8493-0114
H Peter LarssonDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, United States.ORCID 0000-0002-1688-2525
University of Miami · USLinköping University · SEUniversity of Calgary · CA

Funding

Polyunsaturated fatty acids as anti-arrhythmic agents.R01HL131461 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BARRO-SORIA, RENE, DYKXHOORN, DEREK MICHAEL · 2016 to 2024
$5.1M
The Facility for Atomic MutagenesisR24NS104617 · NINDS · UNIVERSITY OF IOWA · PI AHERN, CHRISTOPHER A · 2018 to 2021
$1.0M
NHLBI NIH HHS R01 HL131461NIH HHS R01HL131461NINDS NIH HHS R24 NS104617
6 · The paper itself

Abstract

Voltage-gated potassium (K

Indexed as

Long QT SyndromePotassium Channels, Voltage-GatedArrhythmias, CardiacFatty Acids, UnsaturatedHumansKCNQ1 Potassium ChannelPotassium ChannelsTyrosineFatty Acids, UnsaturatedKCNQ1 Potassium ChannelPotassium ChannelsPotassium Channels, Voltage-GatedTyrosinelong QT syndromemolecular biophysicspolyunsaturated fatty acidspotassium channelstructural biologyxenopus

Identifiers

PMID37350568
PMCPMC10328494
OpenAlexW4381715764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.