Evidence map›Paper›PMID 37349905›Full record

ReviewJournal of cellular and molecular medicine2023

Mechanisms of portal vein tumour thrombus formation and development in patients with hepatocellular carcinoma.

Zhenli Li, Mingda Zhao, Xingshun Qi, Yufu Tang, Shuqun Cheng

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

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  14. The Systemic Immune-Inflammation Index Predicts Portal Vein Tumor Thrombosis and Informs a Clinical Nomogram in HBV-Related Hepatocellular Carcinoma.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Zhenli LiDepartment of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0000-0002-3997-2187
Mingda ZhaoDepartment of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China.
Xingshun QiDepartment of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China.
Yufu TangDepartment of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China.
Shuqun ChengSixth Department of Liver Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
General Hospital of Shenyang Military Region · CNDalian Medical University · CNJiamusi University · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common and aggressive human malignancies worldwide. Portal vein tumour thrombus (PVTT) is considered one of most fearful complications of HCC and is strongly associated with a poor prognosis. Clarification of the mechanisms underlying the formation and development of PVTT is crucial for developing novel therapeutic strategies for HCC patients. Several studies have been made to uncover that tumour microenvironment, stem cells, abnormal gene expression and non-coding RNAs deregulation are associated with PVTT in patients with HCC in the last decade. However, the exact molecular mechanisms of PVTT in patients with HCC are still largely unknown. In the present review, we briefly summarized the molecular mechanisms underlying the formation and development of PVTT in HCC.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsThrombosisHumansPortal VeinRetrospective StudiesTreatment OutcomeTumor Microenvironmenthepatocellular carcinoma (HCC)mechanismportal vein tumour thrombus (PVTT)

Identifiers

PMID37349905
PMCPMC10399540
OpenAlexW4381716161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.