Evidence map›Paper›PMID 37349819›Full record

Trial reportMalaria journal2023

Anopheles vector distribution and malaria transmission dynamics in Gbêkê region, central Côte d'Ivoire.

Alphonsine A Koffi, Soromane Camara, Ludovic P Ahoua Alou, Welbeck A Oumbouke, Rosine Z Wolie, Innocent Z Tia, Eleanore D Sternberg, Florent H A Yapo, Fernand M Koffi, Serge B Assi and 3 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Alphonsine A KoffiInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Soromane CamaraInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire. soromanec@gmail.com.
Ludovic P Ahoua AlouInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Welbeck A OumboukeVector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.
Rosine Z WolieVector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.
Innocent Z TiaVector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.
Eleanore D SternbergTropical Health LLP, London, UK.
Florent H A YapoVector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.
Fernand M KoffiVector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.
Serge B AssiInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Jackie CookMRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Matthew B ThomasDepartment of Entomology & Nematology, The University of Florida, Gainesville, FL, USA.
Raphael N'GuessanInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Institut National de Santé Publique · CILondon School of Hygiene & Tropical Medicine · GBInnovative Vector Control Consortium · GBUniversité Alassane Ouattara · CIUniversité Félix Houphouët-Boigny · CIUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA better understanding of vector distribution and malaria transmission dynamics at a local scale is essential for implementing and evaluating effectiveness of vector control strategies. Through the data gathered in the framework of a cluster randomized controlled trial (CRT) evaluating the In2Care (Wageningen, Netherlands) Eave Tubes strategy, the distribution of the Anopheles vector, their biting behaviour and malaria transmission dynamics were investigated in Gbêkê region, central Côte d'Ivoire.

methodsFrom May 2017 to April 2019, adult mosquitoes were collected monthly using human landing catches (HLC) in twenty villages in Gbêkê region. Mosquito species wereidentified morphologically. Monthly entomological inoculation rates (EIR) were estimated by combining the HLC data with mosquito sporozoite infection rates measured in a subset of Anopheles vectors using PCR. Finally, biting rate and EIR fluctuations were fit to local rainfall data to investigate the seasonal determinants of mosquito abundance and malaria transmission in this region.

resultsOverall, Anopheles gambiae, Anopheles funestus, and Anopheles nili were the three vector complexes found infected in the Gbêkê region, but there was a variation in Anopheles vector composition between villages. Anopheles gambiae was the predominant malaria vector responsible for 84.8% of Plasmodium parasite transmission in the area. An unprotected individual living in Gbêkê region received an average of 260 [222-298], 43.5 [35.8-51.29] and 3.02 [1.96-4] infected bites per year from An. gambiae, An. funestus and An. nili, respectively. Vector abundance and malaria transmission dynamics varied significantly between seasons and the highest biting rate and EIRs occurred in the months of heavy rainfall. However, mosquitoes infected with malaria parasites remained present in the dry season, despite the low density of mosquito populations.

conclusionThese results demonstrate that the intensity of malaria transmission is extremely high in Gbêkê region, especially during the rainy season. The study highlights the risk factors of transmission that could negatively impact current interventions that target indoor control, as well as the urgent need for additional vector control tools to target the population of malaria vectors in Gbêkê region and reduce the burden of the disease.

Indexed as

AnophelesBites and StingsMalariaAdultAnimalsCote d'IvoireHumansMosquito VectorsSeasonsAnopheles vectorCôte d’IvoireInsecticide resistanceMalaria transmission

Identifiers

PMID37349819
PMCPMC10288776
OpenAlexW4381687487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.