ArticleInternational journal of retina and vitreous2023
Retinal OCT findings in acute central retinal artery occlusion of varying severity at different disease stages - a retrospective, observational study.
Article in International journal of retina and vitreous, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Spontaneous Head Turn in Central Retinal Artery Occlusion With Nasal Cilioretinal Artery Sparing: A Case Report.The American journal of case reports · 2026Article
- Retinal, Vascular, and Choroidal Remodeling After Non-Reperfused Central Retinal Artery Occlusion: A Longitudinal OCT Study.Diagnostics (Basel, Switzerland) · 2026Article
- Systemic Inflammation and Structural Retinal Damage on OCT in Acute Non-Arteritic Central Retinal Artery Occlusion-A Retrospective Study.International journal of molecular sciences · 2026Article
- Optical coherence tomography findings in acute central retinal artery occlusion and their association with visual outcomes.International journal of retina and vitreous · 2025Article
- Optical coherence tomography in the emergency department setting: a case series.American journal of ophthalmology case reports · 2025Article
- Central Retinal Artery Occlusion in Acute Care: Current Practices and Emerging Therapies.Cureus · 2025Review
- Correlation of visual acuity changes and optical coherence tomography imaging in patients with central retinal artery occlusion post-arterial thrombolysis.Scientific reports · 2025Article
- Early prostaglandin EFrontiers in ophthalmology · 2025Article
- Retinal Artery Occlusion: A Review of Current Management Practices.Journal of ophthalmic & vision research · 2024Review
- Central retinal artery occlusion: a stroke of the eye.Eye (London, England) · 2024Review
- OCTDL: Optical Coherence Tomography Dataset for Image-Based Deep Learning Methods.Scientific data · 2024Article
- Internal limiting membrane separation and posterior vitreous hyperreflective dots: novel OCT findings in Purtscher-like retinopathy.BMC ophthalmology · 2024Article
- Successful Treatment of Central Retinal Artery Occlusion With Tissue Plasminogen Activator Followed by Recurrent Retinal Ischemia.Journal of vitreoretinal diseasesArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo study the optical coherence tomography (OCT) changes in eyes with acute central retinal artery occlusion (CRAO) of different severity and at different disease stages.
methodsThe study included acute CRAO cases of < 7 days duration, imaged on OCT at various time points. Based on the OCT findings at presentation, cases were classified into three severity groups: mild, moderate, and severe. OCT scans were evaluated and classified into four-time intervals based on symptom duration.
resultsThere were 39 eyes from 38 patients with acute CRAO who underwent 96 OCT scans. At presentation, the study had 11, 16, and 12 cases of mild, moderate, and severe CRAO, respectively. Middle retinal layer opacification was more common in mild CRAO cases, which caused inner retinal layer thinning over time. Moderate CRAO cases had total inner retinal layer opacification, which resulted in retinal thinning over time. Prominent middle limiting membrane (p-MLM) sign was seen in mild and moderate CRAO eyes while were not visualised in severe CRAO. This sign gradually faded out over time. Other OCT findings in higher grades of CRAO included inner retinal fluid, neurosensory detachment, internal limiting membrane detachment, hyperreflective foci, and posterior vitreous opacities. Regardless of the CRAO grade, the final end-point seen was inner retinal layer thinning over time.
conclusionOCT in CRAO is a useful for determining the severity of retinal ischemia, disease stage, tissue damage mechanism, and final visual outcome. More prospective studies analysing a larger number of cases at fixed time points will be required in the future.
trial registrationTrial Registration Number: Not applicable.
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