Evidence map›Paper›PMID 37349739›Full record

SynthesisWorld journal of surgical oncology2023

Prognostic value of consolidation-to-tumor ratio on computed tomography in NSCLC: a meta-analysis.

Yongming Wu, Wenpeng Song, Denian Wang, Junke Chang, Yan Wang, Jie Tian, Sicheng Zhou, Yingxian Dong, Jing Zhou, Jue Li and 2 more

Open access · goldAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in World journal of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yongming Wu *Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wenpeng Song *Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Denian Wang *Precision Medicine Center, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Junke ChangDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yan WangDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jie TianDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Sicheng ZhouDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yingxian DongDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jing ZhouDepartment of Respiratory and Critical Care Medicine, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.
Jue LiDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Ziyi ZhaoDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Guowei CheDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China. cheguoweixw@126.com.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough several studies have confirmed the prognostic value of the consolidation to tumor ratio (CTR) in non-small cell lung cancer (NSCLC), there still remains controversial about it.

methodsWe systematically searched the PubMed, Embase, and Web of Science databases from inception to April, 2022 for eligible studies that reported the correlation between CTR and prognosis in NSCLC. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) were extracted and pooled to assess the overall effects. Heterogeneity was estimated by I

resultsA total of 29 studies published between 2001 and 2022 with 10,347 patients were enrolled. The pooled results demonstrated that elevated CTR was associated with poorer overall survival (HR = 1.88, 95% CI 1.42-2.50, P < 0.01) and disease-free survival (DFS)/recurrence-free survival (RFS)/progression-free survival (PFS) (HR = 1.42, 95% CI 1.27-1.59, P < 0.01) in NSCLC. According to subgroup analysis by the cut-off value of CTR and histology type, both lung adenocarcinoma and NSCLC patients who had a higher CTR showed worse survival. Subgroup analysis stratified by country revealed that CTR was a prognostic factor for OS and DFS/RFS/PFS in Chinese, Japanese, and Turkish patients.

conclusionsIn NSCLC patients with high CTR, the prognosis was worse than that with low CTR, indicating that CTR may be a prognostic factor.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsHumansPrognosisProportional Hazards ModelsTomographyConsolidation to tumor ratioMeta-analysisNon-small cell lung cancerPrognostic

Identifiers

PMID37349739
PMCPMC10286506
OpenAlexW4381716147

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.