Evidence map›Paper›PMID 37349287›Full record

ArticleNature communications2023

A magnetic hydrogel for the efficient retrieval of kidney stone fragments during ureteroscopy.

T Jessie Ge, Daniel Massana Roquero, Grace H Holton, Kathleen E Mach, Kris Prado, Hubert Lau, Kristin Jensen, Timothy C Chang, Simon Conti, Kunj Sheth and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Bio-Inspired Micro-Fin-Assisted Multi-Modal Vascular Intervention.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. [Stones in the lower pole and their treatment].Urologie (Heidelberg, Germany) · 2025
    Article
  11. Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  12. Review
  13. Article
  14. The magic of MagSToNE.Nature reviews. Urology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

T Jessie GeDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Daniel Massana RoqueroDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Grace H HoltonDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Kathleen E MachDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Kris PradoDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Hubert LauVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, 94304, USA.
Kristin JensenVeterans Affairs Palo Alto Health Care System, Palo Alto, CA, 94304, USA.
Timothy C ChangDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Simon ContiDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Kunj ShethDepartment of Urology, Stanford University, Stanford, CA, 94305, USA.
Shan X WangDepartment of Materials Science and Engineering, Stanford University, Stanford, CA, 94305, USA.ORCID 0000-0001-8420-9554
Joseph C LiaoDepartment of Urology, Stanford University, Stanford, CA, 94305, USA. jliao@stanford.edu.ORCID 0000-0003-2448-5463
VA Palo Alto Health Care System · USStanford University · US

Funding

The Stanford Pre-Renal Initiative: Undergraduate Training in Kidney HealthR25DK122957 · NIDDK · STANFORD UNIVERSITY · PI BHALLA, VIVEK · 2020 to 2024
$588k
MagSToNE - a magnetic system for kidney stone fragment eliminationR21DK131776 · NIDDK · STANFORD UNIVERSITY · PI LIAO, JOSEPH C, WANG, SHAN X. · 2021 to 2022
$435k
NIDDK NIH HHS R21 DK131776NIDDK NIH HHS R25 DK122957
6 · The paper itself

Abstract

Only 60-75% of conventional kidney stone surgeries achieve complete stone-free status. Up to 30% of patients with residual fragments <2 mm in size experience subsequent stone-related complications. Here we demonstrate a stone retrieval technology in which fragments are rendered magnetizable with a magnetic hydrogel so that they can be easily retrieved with a simple magnetic tool. The magnetic hydrogel facilitates robust in vitro capture of stone fragments of clinically relevant sizes and compositions. The hydrogel components exhibit no cytotoxicity in cell culture and only superficial effects on ex vivo human urothelium and in vivo mouse bladders. Furthermore, the hydrogel demonstrates antimicrobial activity against common uropathogens on par with that of common antibiotics. By enabling the efficient retrieval of kidney stone fragments, our method can lead to improved stone-free rates and patient outcomes.

Indexed as

Kidney CalculiUreteroscopyAnimalsHumansHydrogelsMagnetic PhenomenaMagneticsMiceHydrogels

Identifiers

PMID37349287
PMCPMC10287666
OpenAlexW4381682104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.