Evidence map›Paper›PMID 37348600›Full record

ArticleContemporary clinical trials2023

Electronic health record based population health management to optimize care in CKD: Design of the Kidney Coordinated HeAlth Management Partnership (K-CHAMP) trial.

Manisha Jhamb, Melanie R Weltman, Jonathan G Yabes, Sanjana Kamat, Susan M Devaraj, Gary S Fischer, Bruce L Rollman, Thomas D Nolin, Khaled Abdel-Kader

Registry-linked trialOpen access · hybridAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03832595 (Kidney Coordinated Health Management Partnership), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03832595 nacompletednot on this map

Kidney Coordinated Health Management Partnership

TypeinterventionalSponsorUniversity of PittsburghRan2019 to 2023Enrolled1,596ConditionsChronic Kidney DiseasesArmsEHR-based PHM, Usual Care
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Population Health Management for Improving Kidney Health Outcomes.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Manisha JhambRenal and Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America. Electronic address: jhambm@upmc.edu.
Melanie R WeltmanRenal-Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
Jonathan G YabesCenter for Research on Heath Care, Division of General Internal Medicine, Department of Medicine and Biostatistics, University of Pittsburgh, Pittsburgh, PA, United States of America.
Sanjana KamatRenal and Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Susan M DevarajRenal and Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Gary S FischerDepartment of Medicine and Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, United States of America.
Bruce L RollmanCenter for Research on Heath Care, Division of General Internal Medicine, Department of Medicine and Biostatistics, University of Pittsburgh, Pittsburgh, PA, United States of America; Center for Behavioral Health, Media, and Technology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Thomas D NolinRenal and Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America; Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, United States of America.
Khaled Abdel-KaderDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · USVanderbilt University Medical Center · US

Funding

PopulAtioN health management to OPTImize Care in CKD (PANOPTIC-CKD)R01DK116957 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ABDEL-KADER, KHALED A, JHAMB, MANISHA · 2018 to 2022
$3.2M
Renal and Epithelial Biology Training ProgramT32DK061296 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2002 to 2022
$3.1M
OPTIMIZing carE in Chronic Kidney Disease (OPTIMIZE CKD)R18DK118460 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JHAMB, MANISHA · 2018 to 2020
$305k
NIDDK NIH HHS R01 DK116957NIDDK NIH HHS R18 DK118460NIDDK NIH HHS T32 DK061296
6 · The paper itself

Abstract

Primary care physicians (PCPs) provide the majority of medical care to patients with non-dialysis dependent CKD. However, PCPs report numerous limitations to providing expert CKD care, including poor patient education, inadequate diagnostic evaluation, suboptimal use of medications, and time limitations. The Kidney Coordinated HeAlth Management Partnership (Kidney CHAMP) trial is a cluster randomized controlled trial to evaluate the effectiveness of a novel centralized electronic health records (EHR)-delivered population health management (PHM) strategy for high-risk CKD patients on patient care, safety, and other outcomes of interest to patients, providers, and payors. Over a 42-month period, the trial will compare the effectiveness of a multifaceted intervention that combines early identification of high-risk patients, timely nephrology guidance, pharmacist-led medication management services, and CKD patient education to usual care and enroll 1650 high-risk CKD patients from 100 primary care practices. The primary outcome will be ≥40% decline in estimated glomerular filtration rate (eGFR) or end stage kidney disease. Key secondary outcomes will include blood pressure, renin-angiotensin aldosterone system inhibitors use, and exposure to potentially unsafe medications. If successful, our treatment approach could improve CKD care delivery and safety, resource allocation, and adoption of evidence-based CKD guideline-concordant care.

Indexed as

Population Health ManagementRenal Insufficiency, ChronicDelivery of Health CareElectronic Health RecordsGlomerular Filtration RateHumansKidneyRandomized Controlled Trials as TopicCKD careE-consultElectronic health recordPopulation health management

Identifiers

PMID37348600
PMCPMC10529809
OpenAlexW4381433294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.