Evidence map›Paper›PMID 37348145›Full record

ArticleVirology2023

Host ranges of Sf-rhabdoviruses harbored by lepidopteran insects and insect cell lines.

Mark T Menghini, Christoph Geisler, Ajay B Maghodia, Hoai J Hallam, Steven L Denton, Jason P Gigley, Donald L Jarvis

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mark T MenghiniDepartment of Molecular Biology, University of Wyoming, Laramie, WY, USA.
Christoph GeislerGlycoBac, LLC, Laramie, WY, USA.
Ajay B MaghodiaGlycoBac, LLC, Laramie, WY, USA.
Hoai J HallamGlycoBac, LLC, Laramie, WY, USA.
Steven L DentonDepartment of Molecular Biology, University of Wyoming, Laramie, WY, USA.
Jason P GigleyDepartment of Molecular Biology, University of Wyoming, Laramie, WY, USA.
Donald L JarvisDepartment of Molecular Biology, University of Wyoming, Laramie, WY, USA; GlycoBac, LLC, Laramie, WY, USA. Electronic address: dljarvis@uwyo.edu.
University of Wyoming · US

Funding

Glycoengineered insect cells for commercial biologics manufacturingR44GM102982 · NIGMS · GLYCOBAC, LLC · PI BLAIR, CAROL D, JARVIS, DONALD L. · 2016 to 2017
$940k
Insect cell lines for glycoprotein structural biology and mannose-dependent protein drugsR43GM136071 · NIGMS · GLYCOBAC, LLC · PI BLAIR, CAROL D, JARVIS, DONALD L. · 2020 to 2020
$225k
NIGMS NIH HHS R43 GM136071NIGMS NIH HHS R44 GM102982
6 · The paper itself

Abstract

Cell lines derived from Spodoptera frugiperda (Sf), which are the most widely used hosts in the baculovirus-insect cell system, are contaminated with Sf-rhabdoviruses (Sf-RVs). In this study, we identified a closely related virus (Sf-CAT-RV) in the caterpillar species used to isolate the original Sf cell line. We then evaluated the Sf-RV and Sf-CAT-RV host ranges, found Sf-CAT-RV could infect Vero cells, and obtained results suggesting both variants can infect mouse ear fibroblasts. In addition, we found both variants could establish pantropic infections in severely immunocompromised (RAG2/IL2RG

Indexed as

Host SpecificityRhabdoviridaeSpodopteraAnimalsCell LineChlorocebus aethiopsDNA-Binding ProteinsImmunocompromised HostLarvaMiceReceptors, Interleukin-2Vero CellsDNA-Binding ProteinsRag2 protein, mouseReceptors, Interleukin-2Adventitious viral contaminationBaculovirus-insect cell expression systemBiosafetyInsect cell linesSf-rhabdovirus

Identifiers

PMID37348145
PMCPMC10528406
OpenAlexW4380447239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.