Evidence map›Paper›PMID 37348142›Full record

ArticleThe journal of physical chemistry. B2023

Excluded Volume and Weak Interactions in Crowded Solutions Modulate Conformations and RNA Binding of an Intrinsically Disordered Tail.

Madison A Stringer, Jasmine Cubuk, J Jeremías Incicco, Debjit Roy, Kathleen B Hall, Melissa D Stuchell-Brereton, Andrea Soranno

Open access · hybridAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Residue-level mapping of crowding effects on protein phase separation.Protein science : a publication of the Protein Society · 2026
    Article
  3. Review
  4. Article
  5. A coarse-grained model for disordered proteins under crowded conditions.Protein science : a publication of the Protein Society · 2025
    Article
  6. Protein-RNA condensation kinetics via filamentous nanoclusters.Protein science : a publication of the Protein Society · 2025
    Article
  7. PEG-mCherry interactions beyond classical macromolecular crowding.Protein science : a publication of the Protein Society · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Madison A StringerDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.
Jasmine CubukDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.
J Jeremías InciccoDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.
Debjit RoyDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.
Kathleen B HallDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.ORCID 0000-0003-2276-0310
Melissa D Stuchell-BreretonDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.
Andrea SorannoDepartment of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 Euclid Avenue, Saint Louis, Missouri 63110, United States.ORCID 0000-0001-8394-7993
Washington University in St. Louis · US

Funding

A multipronged investigation of SARS-CoV-2 genome packagingR01AI163142 · NIAID · WASHINGTON UNIVERSITY · PI Andrea Soranno · 2022 to 2026
$3.1M
NIAID NIH HHS R01 AI163142
6 · The paper itself

Abstract

The cellular milieu is a solution crowded with a significant concentration of different components (proteins, nucleic acids, metabolites,

Indexed as

COVID-19HumansNucleocapsid ProteinsPolyethylene GlycolsProtein ConformationRNASARS-CoV-2Nucleocapsid ProteinsPolyethylene GlycolsRNA

Identifiers

PMID37348142
PMCPMC10331728
OpenAlexW4381716025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.