Evidence map›Paper›PMID 37347557›Full record

ReviewCurrent protocols2023

The Rat Genome Database: Genetic, Genomic, and Phenotypic Data Across Multiple Species.

Stanley J F Laulederkind, G Thomas Hayman, Shur-Jen Wang, Mary L Kaldunski, Mahima Vedi, Wendy M Demos, Monika Tutaj, Jennifer R Smith, Logan Lamers, Adam C Gibson and 6 more

Abstract readReview
In one paragraph

Review in Current protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Xenbase: A Guide to the Xenopus Genetics and Genomics Knowledgebase.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Rat models of musculoskeletal lysosomal storage disorders and their role in pre-clinical evaluation of gene therapy approaches.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  6. Establishing the hybrid rat diversity program: a resource for dissecting complex traits.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Stanley J F LaulederkindDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
G Thomas HaymanDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Shur-Jen WangDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Mary L KaldunskiDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Mahima VediDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Wendy M DemosDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Monika TutajDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Jennifer R SmithDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Logan LamersDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Adam C GibsonDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Ketaki ThoratDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Jyothi ThotaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Marek A TutajDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Jeffrey L de PonsDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Melinda R DwinellDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Anne E KwitekDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Funding

RAT GENOME DATABASER01HL064541 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ANNE E. KWITEK · 1999 to 2026
$50.0M
Text mining in the CloudU24HG010859 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CAROL J BULT, PAUL Warren STERNBERG · 2019 to 2026
$42.0M
NHGRI NIH HHS U24 HG010859NHLBI NIH HHS R01 HL064541
6 · The paper itself

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, https://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes, cellular components, and chemical interactions for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat and other species. © 2023 Wiley Periodicals LLC. Basic Protocol 1: Navigating the Rat Genome Database (RGD) home page Basic Protocol 2: Using the RGD search functions Basic Protocol 3: Searching for quantitative trait loci Basic Protocol 4: Using the RGD genome browser (JBrowse) to find phenotypic annotations Basic Protocol 5: Using OntoMate to find gene-disease data Basic Protocol 6: Using MOET to find gene-ontology enrichment Basic Protocol 7: Using OLGA to generate gene lists for analysis Basic Protocol 8: Using the GA tool to analyze ontology annotations for genes Basic Protocol 9: Using the RGD InterViewer tool to find protein interaction data Basic Protocol 10: Using the RGD Variant Visualizer tool to find genetic variant data Basic Protocol 11: Using the RGD Disease Portals to find disease, phenotype, and other information Basic Protocol 12: Using the RGD Phenotypes & Models Portal to find qualitative and quantitative phenotype data and other rat strain-related information Basic Protocol 13: Using the RGD Pathway Portal to find disease and phenotype data via molecular pathways.

Indexed as

GenomicsQuantitative Trait LociAnimalsDatabases, ProteinHumansOligopeptidesPhenotypeRatsOligopeptidesdatabasegeneontologyquantitative trait locusrat

Identifiers

PMID37347557
PMCPMC10335880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.