Evidence map›Paper›PMID 37347515›Full record

ArticleeLife2023

Response to comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish,

Yutian Li, Anish A Sarma, Iris T Lee, Fayth Hui Tan, Michael J Abrams, Zevin J Condiotte, Martin Heithe, Misha Raffiee, John O Dabiri, David A Gold and 1 more

Open access · goldAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yutian LiDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Anish A SarmaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Iris T LeeDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Fayth Hui TanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Michael J AbramsDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Zevin J CondiotteDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Martin HeitheDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Misha RaffieeGraduate Aerospace Laboratories and Mechanical Engineering, California Institute of Technology, Pasadena, United States.
John O DabiriGraduate Aerospace Laboratories and Mechanical Engineering, California Institute of Technology, Pasadena, United States.
David A GoldDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Lea GoentoroDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0002-3904-0195
California Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously we reported evidence that a regenerative response in the appendages of moon jellyfish, fruit flies, and mice can be promoted by nutrient modulation (Abrams et al., 2021). Sustar and Tuthill subsequently reported that they had not been able to reproduce the induced regenerative response in flies (Sustar and Tuthill, 2023). Here we discuss that differences in the amputation method, treatment concentrations, age of the animals, and stress management explain why they did not observe a regenerative response in flies. Typically, 30-50% of treated flies showed response in our assay.

Indexed as

DrosophilaScyphozoaAnimalsMiceNutrientsNutrientsappendageD. melanogasterevolutionary biologyinsulinleucinemoon jellyfishmouseregenerationregenerative medicinestem cells

Identifiers

PMID37347515
PMCPMC10287153
OpenAlexW4381598709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.