Evidence map›Paper›PMID 37347268›Full record

ArticleJournal of the Royal Society of Medicine2023

Trends in SARS-CoV-2 infection and vaccination in school staff, students and their household members from 2020 to 2022 in Wales, UK: an electronic cohort study.

Emily Lowthian, Hoda Abbasizanjani, Stuart Bedston, Ashley Akbari, Laura Cowley, Richard Fry, Rhiannon K Owen, Joe Hollinghurst, Igor Rudan, Jillian Beggs and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Royal Society of Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. How can the NHS be funded?Journal of the Royal Society of Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Emily LowthianPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.ORCID 0000-0001-9362-0046
Hoda AbbasizanjaniPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.ORCID 0000-0002-9575-4758
Stuart BedstonPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.ORCID 0000-0002-5635-5957
Ashley AkbariPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.ORCID 0000-0003-0814-0801
Laura CowleyPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.ORCID 0000-0002-7757-4219
Richard FryPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.
Rhiannon K OwenPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.
Joe HollinghurstPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.ORCID 0000-0002-3556-2017
Igor RudanCentre for Global Health, Usher Institute, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Jillian BeggsUsher Institute, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Emily MarchantPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.
Fatemeh TorabiPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.
Simon de LusignanNuffield Department of Primary Care Health Sciences, University of Oxford, OX2 6GG, UK.
Tom CrickDepartment of Education & Childhood Studies, School of Social Sciences, Faculty of Humanities and Social Sciences, Swansea University, SA2 8PP, UK.ORCID 0000-0001-5196-9389
Graham MooreDECIPHer, SPARK, Cardiff University, Cardiff, CF24 4HQ, UK.
Aziz SheikhUsher Institute, The University of Edinburgh, Edinburgh, EH8 9AG, UK.
Ronan A LyonsPopulation Data Science, Swansea University Medical School, Faculty of Medicine, Health and Life Science, Swansea University, SA2 8PP, UK.
Swansea University · GBUniversity of Edinburgh · GBCardiff University · GBUniversity of Oxford · GB

Funding

Medical Research Council MC_PC_20058Medical Research Council MR/V028367/1Wellcome Trust
6 · The paper itself

Abstract

objectivesWe investigated SARS-CoV-2 infection trends, risk of SARS-CoV-2 infection and COVID-19 vaccination uptake among school staff, students and their household members in Wales, UK.

designSeven-day average of SARS-CoV-2 infections and polymerase chain reaction tests per 1000 people daily, cumulative incidence of COVID-19 vaccination uptake and multi-level Poisson models with time-varying covariates.

settingNational electronic cohort between September 2020 and May 2022 when several variants were predominant in the UK (Alpha, Delta and Omicron).

participantsSchool students aged 4 to 10/11 years (primary school and younger middle school,

main outcome measuresSARS-CoV-2 infection and COVID-19 vaccination uptake.

resultsSchool students had a sustained period of high infection rates compared with household members after August 2021. Primary schedule vaccination uptake was highest among staff (96.3%) but lower for household members (72.2%), secondary and older middle school students (59.8%), and primary and younger middle school students (3.3%). Multi-level Poisson models showed that vaccination was associated with a lower risk of SARS-CoV-2 infection. The Delta variant posed a greater infection risk for students than the Alpha variant. However, Omicron was a larger risk for staff and household members.

conclusionsPublic health bodies should be informed of the protection COVID-19 vaccines afford, with more research being required for younger populations. Furthermore, schools require additional support in managing new, highly transmissible variants. Further research should examine the mechanisms between child deprivation and SARS-CoV-2 infection.

Indexed as

COVID-19ChildCohort StudiesCOVID-19 VaccinesElectronicsHumansSARS-CoV-2SchoolsStudentsVaccinationWalesCOVID-19 VaccinesCOVID-19pandemicpopulation healthschoolssocial restrictions

Identifiers

PMID37347268
PMCPMC10767617
OpenAlexW4381598083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.