Evidence map›Paper›PMID 37346976›Full record

ArticleMolecular therapy. Nucleic acids2023

MutSα and MutSβ as size-dependent cellular determinants for prime editing in human embryonic stem cells.

Ju-Chan Park, Yun-Jeong Kim, Jun Hee Han, Dayeon Kim, Mihn Jeong Park, Jumee Kim, Hyeon-Ki Jang, Sangsu Bae, Hyuk-Jin Cha

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ju-Chan ParkCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Yun-Jeong KimCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Jun Hee HanDepartment of Chemistry, Hanyang University, Seoul, Republic of Korea.
Dayeon KimCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Mihn Jeong ParkCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Jumee KimCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Hyeon-Ki JangDivision of Chemical Engineering and Bioengineering, College of Art Culture and Engineering, Kangwon National University, Chuncheon, South Korea.
Sangsu BaeCollege of Medicine, Seoul National University, Seoul, Republic of Korea.
Hyuk-Jin ChaCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Seoul National University · KRHanyang University · KRKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise genome editing in human pluripotent stem cells (hPSCs) has potential applications in isogenic disease modeling and

Indexed as

DNA damage repairgenome editinghuman embryonic stem cellshuman pluripotent stem cellsMMRMT: RNA/DNA editing;MutSαMutSβprime editor

Identifiers

PMID37346976
PMCPMC10280094
OpenAlexW4377024399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.