Evidence map›Paper›PMID 37346878›Full record

ReviewBasic and clinical neuroscience

Neurostimulation as a Putative Method for the Treatment of Drug-resistant Epilepsy in Patient and Animal Models of Epilepsy.

Fatemeh Bakhtiarzadeh, Meysam Zare, Zahra Ghasemi, Samaneh Dehghan, Azam Sadeghin, Mohammad Taghi Joghataei, Nooshin Ahmadirad

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fatemeh BakhtiarzadehDepartment of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID https://orcid.org/0000-0002-2969-8145
Meysam ZareDepartment of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID https://orcid.org/0000-0001-9181-9203
Zahra GhasemiLunenfeld-Tanenbaum Research Institute, Toronto, Canada.ORCID https://orcid.org/0000-0002-9191-3563
Samaneh DehghanStem cell and Regenerative Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9070-6792
Azam SadeghinDepartment of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Mohammad Taghi JoghataeiDepartment of Anatomy and Neuroscience, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-0492-8239
Nooshin AhmadiradCellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9853-8180
Iran University of Medical Sciences · IRTarbiat Modares University · IRLunenfeld-Tanenbaum Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A patient with epilepsy was shown to have neurobiological, psychological, cognitive, and social issues as a result of recurring seizures, which is regarded as a chronic brain disease. However, despite numerous drug treatments, approximately, 30%-40% of all patients are resistant to antiepileptic drugs. Therefore, newer therapeutic modalities are introduced into clinical practice which involve neurostimulation and direct stimulation of the brain. Hence, we review published literature on vagus nerve stimulation, trigeminal nerve stimulation, applying responsive stimulation systems, and deep brain stimulation (DBS) in animals and epileptic patient with an emphasis on drug-resistant epilepsy.

Indexed as

Deep brain stimulationDrug-resistant epilepsyResponsive stimulation systemTrigeminal nerve stimulationVagus nerve stimulation

Identifiers

PMID37346878
PMCPMC10279981
OpenAlexW4366962731

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.