Evidence map›Paper›PMID 37346366›Full record

ReviewInternational journal of nanomedicine2023

Advances in Therapeutic Applications of Extracellular Vesicles.

Yiming Zhang, Yiming Dou, Yang Liu, Mingyuan Di, Hanming Bian, Xun Sun, Qiang Yang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yiming Zhang *Department of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
Yiming Dou *Department of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
Yang LiuDepartment of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
Mingyuan DiDepartment of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
Hanming BianDepartment of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.
Xun SunDepartment of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.ORCID 0000-0001-6172-4692
Qiang YangDepartment of Spine Surgery, Tianjin Hospital, Tianjin University, Tianjin, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are nanoscale bilayer phospholipid membrane vesicles released by cells. Contained large molecules such as nucleic acid, protein, and lipid, EVs are an integral part of cell communication. The contents of EVs vary based on the cell source and play an important role in both pathological and physiological conditions. EVs can be used as drugs or targets in disease treatment, and changes in the contents of EVs can indicate the progression of diseases. In recent years, with the continuous exploration of the structure, characteristics, and functions of EVs, the potential of engineered EVs for drug delivery and therapy being constantly explored. This review provides a brief overview of the structure, characteristics and functions of EVs, summarizes the advanced application of EVs and outlook on the prospect of it. It is our hope that this review will increase understanding of the current development of medical applications of EVs and help us overcome future challenges.

Indexed as

Extracellular VesiclesNucleic AcidsCell CommunicationDrug Delivery SystemsPhospholipidsNucleic AcidsPhospholipidsadvances applicationsdisease diagnosisengineered exosomeextracellular vesiclenanotherapeutic

Identifiers

PMID37346366
PMCPMC10281276

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.