Evidence map›Paper›PMID 37346094›Full record

ArticleInfluenza and other respiratory viruses2023

Clinical symptoms of SARS-CoV-2 breakthrough infection during the Omicron period in relation to baseline immune status and booster vaccination-A prospective multicentre cohort of health professionals (SURPRISE study).

Philipp Kohler, Baharak Babouee Flury, Sabine Güsewell, Thomas Egger, Onicio Leal, Angela Brucher, Eva Lemmenmeier, Dorette Meier Kleeb, J Carsten Möller, Manuela Ortner and 16 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Influenza and other respiratory viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 9 institutions in 3 countries.

Philipp KohlerDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.ORCID 0000-0003-0427-8934
Baharak Babouee FluryDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Sabine GüsewellDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Thomas EggerDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Onicio LealEpitrack Recife Brazil.
Angela BrucherPsychiatry Services of the Canton of St. Gallen (South) Pfäfers Switzerland.
Eva LemmenmeierClienia Littenheid AG, Private Clinic for Psychiatry and Psychotherapy Littenheid Switzerland.
Dorette Meier KleebDivision of Occupational Health Kantonsspital Baden Baden Switzerland.
J Carsten MöllerCenter for Neurological Rehabilitation Zihlschlacht Switzerland.
Manuela OrtnerRheintal Werdenberg Sarganserland Hospital Group Grabs Switzerland.
Philip RiederHirslanden Clinic Zurich Switzerland.
Markus RuettiFuerstenland Toggenburg Hospital Group Wil Switzerland.
Hans-Ruedi SchmidKantonsspital Baden, Central Laboratory Baden Switzerland.
Reto StockerHirslanden Clinic Zurich Switzerland.
Danielle Vuichard-GysinDivision of Infectious Diseases and Hospital Epidemiology Thurgau Hospital Group Muensterlingen Switzerland.
Oliver SpeerThurgau Hospital Group Institute for Laboratory Medicine Muensterlingen Switzerland.
Benedikt WiggliDivision of Infectious Diseases and Hospital Epidemiology Kantonsspital Baden Baden Switzerland.
Ulrike BesoldGeriatric Clinic St. Gallen St. Gallen Switzerland.
Allison McGeerSinai Health System Toronto Canada.ORCID 0000-0001-5647-6137
Lorenz RischLabormedizinisches Zentrum Dr Risch Ostschweiz AG Buchs Switzerland.
Andrée FriedlThurgau Hospital Group Institute for Laboratory Medicine Muensterlingen Switzerland.
Matthias SchlegelDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Pietro VernazzaDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Christian R KahlertDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.
Stefan P KusterDivision of Infectious Diseases and Hospital Epidemiology Cantonal Hospital St Gallen St Gallen Switzerland.ORCID 0000-0002-0525-6529
SURPRISE Study Group
University of St.Gallen · CHKantonsspital Baden · CHSpital Thurgau (Switzerland) · CHKlinik Hirslanden · CHHirslanden Private Hospital Group · CHRehaklinik Zihlschlacht · CHSinai Health System · CAUniversity of Bern · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of different types of pre-existing immunity on the frequency of clinical symptoms caused by the SARS-CoV-2 breakthrough infection were prospectively assessed in healthcare workers during the Omicron period. Among 518 participants, hybrid immunity was associated with symptom reduction for dizziness, muscle or limb pain and headache as compared to vaccination only. Moreover, the frequencies of dizziness, cough and muscle or limb pain were lower in participants who had received a booster vaccine dose. Thus, hybrid immunity appeared to be superior in preventing specific symptoms during breakthrough infection compared to vaccination alone. A booster vaccine dose conferred additional symptom reduction.

Indexed as

COVID-19VaccinesBreakthrough InfectionsDizzinessHealth PersonnelHumansPainProspective StudiesSARS-CoV-2VaccinationVaccinesbreakthrough infectionCovid‐19health professionalssymptomsvaccine

Identifiers

PMID37346094
PMCPMC10279996
OpenAlexW4381429298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.