Evidence map›Paper›PMID 37346071›Full record

ArticleFrontiers in oncology2023

Prognostic value of extrahepatic metastasis on colon cancer with liver metastasis: a retrospective cohort study.

Shuheng Bai, Ling Chen, Guixian Zhu, Wang Xuan, Fengyuan Hu, Wanyi Liu, Wenyang Li, Ning Lan, Min Chen, Yanli Yan and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shuheng BaiDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ling ChenDepartment of Chemotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Guixian ZhuDepartment of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wang XuanDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Fengyuan HuDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wanyi LiuDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wenyang LiDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ning LanDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Min ChenDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yanli YanDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Rong LiDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yiping YangDepartment of Radiotherapy, Radiotherapy Clinical Medical Research Center of Shaanxi Province, Xi'an, China.
Juan RenDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The occurrence of metastasis is a threat to patients with colon cancer (CC), and the liver is the most common metastasis organ. However, the role of the extrahepatic organs in patients with liver metastasis (LM) has not been distinctly demonstrated. Therefore, this research aimed to explore the prognostic value of extrahepatic metastases (EHMs). Methods: In this retrospective study, a total of 13,662 colon patients with LM between 2010 and 2015 were selected from the Surveillance, Epidemiology, and End Results database (SEER). Fine and Gray's analysis and K-M survival analysis were utilized to explore the impacts of the number of sites of EHMs and different sites of EHMs on prognosis. Finally, a prognostic nomogram model based on the number of sites of EHMs was constructed, and a string of validation methods was conducted, including concordance index (C-index), receiver operating characteristic curves (ROC), and decision curve analysis (DCA). Results: Patients without EHMs had better prognoses in cancer-specific survival (CSS) and overall survival (OS) than patients with EHMs ( Conclusion: The number of sites of EHMs was a significant prognostic factor of CC patients with LM. However, the sites of EHMs showed limited impact on survival. Furthermore, a nomogram based on the number of sites of EHMs was constructed to predict the OS of patients with EHMs accurately.

Indexed as

colorectal cancercompeting risk analysisextrahepatic metastasisprognostic modelrisk factorSEER

Identifiers

PMID37346071
PMCPMC10280983

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.