ArticleMicrobial biotechnology2023
Regulation of indole-3-acetic acid biosynthesis and consequences of auxin production deficiency in Serratia plymuthica.
Article in Microbial biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Auxin biosynthesis and signaling drive virulence and plant adaptation in Dickeya dadantii.PLoS pathogens · 2026Article
- NIT24 and NIT29-Dependent Auxin Biosynthesis Promotes Virulence and Auxin-SA Antagonism in Rice During Xanthomonas oryzae pv. oryzae Infection.The plant pathology journal · 2026Article
- Chemotaxis to plant defense compounds in phytopathogens.PLoS pathogens · 2026Article
- Seed-microbiome interactions: Mechanistic insights and utilization toward seed performance for sustainable agriculture.Plant communications · 2026Review
- AnFrontiers in plant science · 2026Article
- From Leaves to Roots: How Foliar IAA Application Alters Fungal Network in the Rhizosphere and Endosphere of Eucommia ulmoides.Current microbiology · 2025Article
- Article
- Carrier-Based Application of Phyto-Benefic and Salt-TolerantPlants (Basel, Switzerland) · 2025Article
- Indole-3-acetic acid (IAA) protectsApplied and environmental microbiology · 2025Article
- Cooperative microbial metabolism enhances tryptophan-mediated insecticide detoxification in the fall armyworm.The ISME journal · 2025Article
- Genomic and phenotypic profiling of anFrontiers in microbiology · 2025Article
- Synthesis and Degradation of the Phytohormone Indole-3-Acetic Acid by the Versatile BacteriumPlants (Basel, Switzerland) · 2024Article
- ScreeningJournal of fungi (Basel, Switzerland) · 2024Article
- Feeling hormonal? Insights into bacterial auxin sensing and its physiological effects.mSystems · 2024Article
- Cover crop root exudates impact soil microbiome functional trajectories in agricultural soils.Microbiome · 2024Article
- Auxin-mediated regulation of susceptibility to toxic metabolites, c-di-GMP levels, and phage infection in the rhizobacteriummSystems · 2024Article
- Cover Crop Root Exudates Impact Soil Microbiome Functional Trajectories in Agricultural Soils.Research square · 2024Article
- Regulation of indole-3-acetic acid biosynthesis and consequences of auxin production deficiency in Serratia plymuthica.Microbial biotechnology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Indole-3-acetic acid (IAA) is emerging as a key intra- and inter-kingdom signal molecule that modulates a wide range of processes of importance during plant-microorganism interaction. However, the mechanisms by which IAA carries out its functions in bacteria as well as the regulatory processes by which bacteria modulate auxin production are largely unknown. Here, we found that IAA synthesis deficiency results in important global transcriptional changes in the broad-range antibiotic-producing rhizobacterium Serratia plymuthica A153. Most pronounced transcriptional changes were observed in various gene clusters for aromatic acid metabolism, including auxin catabolism. To delve into the corresponding molecular mechanisms, different regulatory proteins were biochemically characterized. Among them, a TyrR orthologue was essential for IAA production through the activation of the ipdc gene encoding a key enzyme for IAA biosynthesis. We showed that TyrR specifically recognizes different aromatic amino acids which, in turn, alters the interactions of TyrR with the ipdc promoter. Screening of mutants defective in various transcriptional and post-transcriptional regulators allowed the identification of additional regulators of IAA production, including PigP and quorum sensing-related genes. Advancing our knowledge on the mechanisms that control the IAA biosynthesis in beneficial phytobacteria is of biotechnological interest for improving agricultural productivity and sustainable agricultural development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.