Evidence map›Paper›PMID 37345819›Full record

ArticleJournal of the American Heart Association2023

Optimized Risk Score to Predict Mortality in Patients With Cardiogenic Shock in the Cardiac Intensive Care Unit.

Eric Yamga, Sreekar Mantena, Darin Rosen, Emily M Bucholz, Robert W Yeh, Leo A Celi, Berk Ustun, Neel M Butala

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Profiling of Cardiogenic Shock: Incorporating Machine Learning Into Bedside Management.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Eric YamgaDepartment of Medicine Centre Hospitalier de l'Université de Montréal (CHUM) Montreal QC Canada.ORCID 0000-0002-9911-8070
Sreekar MantenaHarvard Medical School Boston MA USA.ORCID 0000-0002-8834-1461
Darin RosenJohns Hopkins School of Medicine Baltimore MD USA.
Emily M BucholzUniversity of Colorado School of Medicine Aurora CO USA.
Robert W YehHarvard Medical School Boston MA USA.ORCID 0000-0002-0564-4468
Leo A CeliHarvard Medical School Boston MA USA.ORCID 0000-0001-6712-6626
Berk UstunHalıcıoğlu Data Science Institute University of California San Diego CA USA.ORCID 0000-0001-5188-3155
Neel M ButalaUniversity of Colorado School of Medicine Aurora CO USA.ORCID 0000-0001-6937-4041
Harvard University · USBeth Israel Deaconess Medical Center · USCentre Hospitalier de l’Université de Montréal · CAChildren's Hospital Colorado · USJohns Hopkins University · USRocky Mountain MS Center · USUniversity of California San Diego · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Medical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7M
Ethics Core (FABRIC)U54HG012510 · NHGRI · YALE UNIVERSITY · PI MALIN, BRADLEY A. · 2022 to 2025
$11.2M
NHGRI NIH HHS U54 HG012510NIGMS NIH HHS T32 GM007753NIGMS NIH HHS T32 GM144273
6 · The paper itself

Abstract

Background Mortality prediction in critically ill patients with cardiogenic shock can guide triage and selection of potentially high-risk treatment options. Methods and Results We developed and externally validated a checklist risk score to predict in-hospital mortality among adults admitted to the cardiac intensive care unit with Society for Cardiovascular Angiography & Interventions Shock Stage C or greater cardiogenic shock using 2 real-world data sets and Risk-Calibrated Super-sparse Linear Integer Modeling (RiskSLIM). We compared this model to those developed using conventional penalized logistic regression and published cardiogenic shock and intensive care unit mortality prediction models. There were 8815 patients in our training cohort (in-hospital mortality 13.4%) and 2237 patients in our validation cohort (in-hospital mortality 22.8%), and there were 39 candidate predictor variables. The final risk score (termed BOS,MA

Indexed as

Intensive Care UnitsShock, CardiogenicAdultHospital MortalityHumansMiddle AgedRetrospective StudiesRisk Factorscardiogenic shockCICUmachine learningmortalityrisk scoreSCAI shock

Identifiers

PMID37345819
PMCPMC10356069
OpenAlexW4381598428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.