Evidence map›Paper›PMID 37345518›Full record

Observational studyCirculation. Heart failure2023

Change in Caregiver Health-Related Quality of Life From Before to Early After Surgery: SUSTAIN-IT Study.

Sarah Chuzi, Jane E Wilcox, Andrew Kao, John A Spertus, Eileen Hsich, Mary Amanda Dew, Clyde W Yancy, Duc T Pham, Justin Hartupee, Michael Petty and 14 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Circulation. Heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02568930 (SUSTAIN-IT), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02568930 completednot on this map

SUSTAIN-IT: Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support?

TypeobservationalSponsorNorthwestern UniversityRan2015 to 2021Enrolled694ConditionsHeart Failure
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 15 institutions in 3 countries.

Sarah ChuziNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).ORCID 0000-0001-5348-2742
Jane E WilcoxNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).
Andrew KaoSt. Luke's Medical Center, Kansas City, MO (A.K.).
John A SpertusUniversity of Missouri-Kansas City (J.A.S.).ORCID 0000-0002-2839-2611
Eileen HsichCleveland Clinic, OH (E.H.).ORCID 0000-0001-6420-0480
Mary Amanda DewUniversity of Pittsburgh, PA (M.A.D.).
Clyde W YancyNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).ORCID 0000-0001-7271-4166
Duc T PhamNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).ORCID 0000-0003-4443-601X
Justin HartupeeWashington University, St. Louis, MO (J.H.).
Michael PettyUniversity of Minnesota Medical Center, Minneapolis (M.P.).
William CottsAdvocate Christ Medical Center, Oak Lawn, IL (W.C.).
Salpy V PamboukianUniversity of Alabama-Birmingham (S.V.P., J.K.K.).
Francis D PaganiUniversity of Michigan, Ann Arbor (F.D.P.).ORCID 0000-0003-4430-9969
Brent LampertOhio State University, Columbus (B.L.).
Maryl JohnsonUniversity of Wisconsin, Madison (M.J., M.M.).
Margaret MurrayUniversity of Wisconsin, Madison (M.J., M.M.).ORCID 0000-0002-4306-5985
Koji TakedaColumbia University, New York (K.T., M.Y.).ORCID 0000-0001-8263-1911
Melana YuzefpolskayaColumbia University, New York (K.T., M.Y.).ORCID 0000-0003-4729-8943
Scott SilvestryFlorida Hospital, Orlando (S.S.).
James K KirklinUniversity of Alabama-Birmingham (S.V.P., J.K.K.).
Tingqing WuNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).ORCID 0000-0003-2816-6590
Adin-Cristian AndreiNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).
Abigail BaldridgeNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).ORCID 0000-0002-1573-0554
Kathleen L GradyNorthwestern University, Chicago, IL (S.C., J.E.W., C.W.Y., D.T.P., T.W., A.-C.A., A.B., K.L.G.).ORCID 0000-0002-6570-5365
Northwestern University · USUniversity of Alabama at Birmingham · USUniversity of Wisconsin–Madison · USAdventHealth Orlando · USAdvocate Christ Medical Center · USCleveland Clinic · USSaint Luke's Health System · USTakeda (United States) · USThe Ohio State University · USUniversity of Michigan · USUniversity of Minnesota Medical Center · USUniversity of Missouri–Kansas City · USUniversity of Pittsburgh · USWashington University in St. Louis · USYanan University Affiliated Hospital · CN

Funding

Sustaining quality of life of the aged: Heart transplant or mechanical support?R01AG047416 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GRADY, KATHLEEN L · 2015 to 2019
$3.3M
Impact of Disparities Affecting Survival among Advanced Heart Failure Patients and Transplant RecipientsR01HL141892 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HSICH, EILEEN MICHELLE, ISHWARAN, HEMANT · 2018 to 2021
$2.8M
Real time risk prognostication via scalable hazard trees and forestsR01HL164405 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Hemant Ishwaran · 2023 to 2026
$2.3M
NHLBI NIH HHS R01 HL141892NHLBI NIH HHS R01 HL164405NIA NIH HHS R01 AG047416
6 · The paper itself

Abstract

backgroundInformation about health-related quality of life (HRQOL) among caregivers of older patients with heart failure who receive heart transplantation (HT) and mechanical circulatory support (MCS) is sparse. We describe differences and factors associated with change in HRQOL before and early post-surgery among caregivers of older heart failure patients who underwent 3 surgical therapies: HT with pretransplant MCS (HT MCS), HT without pretransplant MCS (HT non-MCS), and long-term MCS.

methodsCaregivers of older patients (60-80 years) from 13 US sites completed the EQ-5D-3 L visual analog scale (0 [worst]-100 [best] imaginable health state) and dimensions before and 3 and 6 months post-surgery. Analyses included linear regression,

resultsAmong 227 caregivers (HT MCS=54, HT non-MCS=76, long-term MCS=97; median age 62.7 years, 30% male, 84% White, 83% spouse/partner), EQ-5D visual analog scale scores were high before (84.8±14.1) and at 3 (84.7±13.0) and 6 (83.9±14.7) months post-surgery, without significant differences among groups or changes over time. Patient pulmonary hypertension presurgery (β=-13.72 [95% CI, -21.07 to -6.36];

conclusionsCaregivers of older patients undergoing heart failure surgeries reported overall high HRQOL before and early post-surgery. Understanding factors associated with caregiver HRQOL may inform decision-making and support needs. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT02568930.

Indexed as

Heart-Assist DevicesHeart FailureHeart TransplantationAgedAged, 80 and overCaregiversFemaleHumansMaleMiddle AgedQuality of Lifeagedcaregiversheart-assist devicesheart failurequality of life

Identifiers

PMID37345518
PMCPMC10482357
OpenAlexW4381597724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.