Evidence map›Paper›PMID 37345259›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2023

Nutrition in the intensive care unit and early recovery influence functional outcomes for survivors of critical illness: A prospective cohort study.

Lindsey E Jubina, Alleyna Locke, Kelly R Fedder, Stacey A Slone, Melissa K Soper, Anna G Kalema, Ashley A Montgomery-Yates, Kirby P Mayer

Open access · bronzeAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lindsey E JubinaDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0003-1891-0013
Alleyna LockeDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, USA.
Kelly R FedderDepartment of Clinical Nutrition, University of Kentucky HealthCare, Lexington, Kentucky, USA.ORCID 0000-0002-4161-1604
Stacey A SloneDr. Bing Zhang Department of Statistics, College of Arts & Sciences, University of Kentucky, Lexington, Kentucky, USA.
Melissa K SoperDivision of Pulmonary, Critical Care and Sleep Medicine, Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Anna G KalemaDivision of Pulmonary, Critical Care and Sleep Medicine, Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Ashley A Montgomery-YatesDivision of Pulmonary, Critical Care and Sleep Medicine, Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0003-2245-1219
Kirby P MayerDepartment of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0003-3844-3846
University of Kentucky · USUniversity of Kentucky HealthCare · US

Funding

Cellular and Physical Function Outcomes Leading to Failed Muscle Recovery After Critical IllnessK23AR079583 · NIAMS · UNIVERSITY OF KENTUCKY · PI Kirby P Mayer · 2022 to 2026
$744k
NIAMS NIH HHS K23 AR079583NIMHD NIH HHS L32 MD017732
6 · The paper itself

Abstract

backgroundPatients who are critically ill may receive suboptimal nutrition that leads to weight loss and increased risk of functional deficits.

methodsOur overarching hypothesis is that nutrition in the intensive care unit (ICU) and the early recovery phase associates with functional outcomes at short-term follow-up. We enrolled adult patients who attended the University of Kentucky ICU recovery clinic (ICU-RC) from November 2021 to June 2022. Patients participated in muscle and functional assessments. Nutrition intake and status during the ICU stay were analyzed. The Subjective Global Assessment and a nutrition questionnaire were used to identify changes in intake, ongoing gastrointestinal symptoms, and patient's access to food at the ICU-RC appointment.

resultsForty-one patients enrolled with a median hospital length of stay (LOS) of 23 days. Patients with 0 days of nil per os (NPO) status throughout hospitalization had a shorter LOS (P = 0.05), were able to complete the five times sit-to-stand test (P = 0.02), and were less likely to experience ICU-acquired weakness (P = 0.04) at short-term follow-up compared with patients with ≥1 day of NPO status. Twenty (48%) patients reported changes in nutrition intake in early recovery compared with before hospitalization. Eight (20%) patients reported symptoms leading to decreased intake and four (10%) reported access to food as a barrier to intake.

conclusionBarriers to nutrition exist during critical illness and persist after discharge, with almost half of patients reporting a change in intake. Inpatient nutrition intake is associated with functional outcomes and warrants further exploration.

Indexed as

Critical IllnessNutritional StatusAdultHumansIntensive Care UnitsLength of StayProspective StudiesSurvivorscalorie deficitcritical care nutritionenteral feedingICU-acquired weaknesspostintensive care syndrome

Identifiers

PMID37345259
PMCPMC11210604
OpenAlexW4381597615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.