Evidence map›Paper›PMID 37345218›Full record

ArticleClinical cardiology2023

Direct admission versus interhospital transfer for revascularisation in non-ST-segment elevation myocardial infarction.

Gijs J van Steenbergen, Jesse P A Demandt, Daniela N Schulz, Pim A Tonino, Lukas Dekker, Iris Vermeer-Gerritzen, Inge F Wijnbergen, Eric J M Thijssen, Luc J H J Theunissen, Eric P C M Heijmen and 3 more

Abstract read
In one paragraph

Article in Clinical cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Timing of invasive strategy in patients with non-ST segment elevation acute myocardial infarction: A nationwide retrospective cohort analysis.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gijs J van SteenbergenCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.ORCID https://orcid.org/0000-0003-0411-7014
Jesse P A DemandtCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Daniela N SchulzCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Pim A ToninoCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Lukas DekkerCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Iris Vermeer-GerritzenCentraal Ziekenfonds (CZ), Tilburg, The Netherlands.
Inge F WijnbergenCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Eric J M ThijssenNetherlands Heart Network (NHN), South-East Brabant, The Netherlands.
Luc J H J TheunissenNetherlands Heart Network (NHN), South-East Brabant, The Netherlands.
Eric P C M HeijmenNetherlands Heart Network (NHN), South-East Brabant, The Netherlands.
Rutger J P HaestNetherlands Heart Network (NHN), South-East Brabant, The Netherlands.
Pieter-Jan VlaarCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Dennis van VeghelCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe differences in outcomes and process parameters for NSTEMI patients who are directly admitted to an intervention centre and patients who are first admitted to a general centre are largely unknown. HYPOTHESIS: There are differences in process indicators, but not for clinical outcomes, for NSTEMI who are directly admitted to an intervention centre and patients who are first admitted to a general centre.

methodsWe aim to compare process indicators, costs and clinical outcomes of non-ST-segment elevation myocardial infarction (NSTEMI) patients stratified by center of first presentation and revascularisation strategy. Hospital claim data from patients admitted with a NSTEMI between 2017 and 2019 were used for this study. Included patients were stratified by center of admission (intervention vs. general center) and subdivided by revascularisation strategy (PCI, CABG, or no revascularisation [noRevasc]). The primary outcome was length of hospital stay. Secondary outcomes included: duration between admission and diagnostic angiography and revascularisation, number of intracoronary procedures, clinical outcomes at 30 days (MACE: all-cause mortality, recurrent myocardial infarction and cardiac readmission) and total costs (accumulation of costs for hospital claims and interhospital ambulance rides).

resultsA total of 9641 NSTEMI events (9167 unique patients) were analyzed of which 5399 patients (56%) were admitted at an intervention center and 4242 patients to a general center. Duration of hospitalization was significantly shorter at direct presentation at an intervention centre for all study groups (5 days [2-11] vs. 7 days [4-12], p < 0.001). For PCI, direct presentation at an intervention center yielded shorter time to diagnostic angiography (1 day [0-2] vs. 1 day [1-2], p < 0.01) and revascularisation (1 day [0-3] vs. 4 days [1-7], p < 0.001) and less intracoronary procedures per patient (2 [1-2] vs. 2 [2-2], p < 0.001). For CABG, time to revascularisation was shorter (8 days [5-12] vs. 10 days [7-14], p < 0.001). Total costs were significantly lower in case of direct presentation in an intervention center for all treatment groups €10.211 (8750-18.192) versus €13.741 (11.588-19.381), p < 0.001) while MACE was similar 11.8% versus 12.4%, p = 0.344).

conclusionNSTEMI patients who were directly presented to an intervention center account for shorter duration of hospitalization, less time to revascularisation, less interhospital transfers, less intracoronary procedures and lower costs compared to patients who present at a general center.

Indexed as

Non-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionHospitalizationHumansLength of StayTreatment Outcomecardiologycardiothoracic surgeryESCNSTEMIpatient valuevalue-based healthcare

Identifiers

PMID37345218
PMCPMC10436781

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.