Evidence map›Paper›PMID 37345184›Full record

ArticleCancers2023

Practical Utility of Liquid Biopsies for Evaluating Genomic Alterations in Castration-Resistant Prostate Cancer.

Seung-Hwan Jeong, Dongsoo Kyung, Hyeong Dong Yuk, Chang Wook Jeong, Wookjae Lee, Jung-Ki Yoon, Hwang-Phill Kim, Duhee Bang, Tae-You Kim, Yoojoo Lim and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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  4. Clinical and Molecular Characteristics ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Seung-Hwan JeongDepartment of Urology, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Dongsoo KyungIMBdx Inc., Seoul 08506, Republic of Korea.
Hyeong Dong YukDepartment of Urology, Seoul National University Hospital, Seoul 03080, Republic of Korea.ORCID 0000-0002-5874-9167
Chang Wook JeongDepartment of Urology, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Wookjae LeeIMBdx Inc., Seoul 08506, Republic of Korea.
Jung-Ki YoonIMBdx Inc., Seoul 08506, Republic of Korea.
Hwang-Phill KimIMBdx Inc., Seoul 08506, Republic of Korea.
Duhee BangDepartment of Chemistry, Yonsei University, Seoul 03722, Republic of Korea.
Tae-You KimIMBdx Inc., Seoul 08506, Republic of Korea.
Yoojoo LimIMBdx Inc., Seoul 08506, Republic of Korea.ORCID 0000-0002-4181-2916
Cheol KwakDepartment of Urology, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Seoul National University Hospital · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional tissue-based assessments of genomic alterations in castration-resistant prostate cancer (CRPC) can be challenging. To evaluate the real-world clinical utility of liquid biopsies for the evaluation of genomic alterations in CRPC, we preemptively collected available plasma samples and archival tissue samples from patients that were being treated for clinically confirmed CRPC. The cell-free DNA (cfDNA) and tumor tissue DNA were analyzed using the AlphaLiquid

Indexed as

castration-resistant prostate cancercfDNAgenomic profilinghomologous recombination repair genesliquid biopsy

Identifiers

PMID37345184
PMCPMC10216019
OpenAlexW4377293822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.