Evidence map›Paper›PMID 37345181›Full record

ArticleCancers2023

The Prognostic Relevance of MRI Characteristics in Myxofibrosarcoma Patients Treated with Neoadjuvant Radiotherapy.

Stefan G van Ravensteijn, Maikel J L Nederkoorn, Tom C P Wal, Yvonne M H Versleijen-Jonkers, Pètra M Braam, Uta E Flucke, Johannes J Bonenkamp, Bart H W Schreuder, Carla M L van Herpen, Johannes H W de Wilt and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Stefan G van RavensteijnDepartment of Medical Oncology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-4069-3932
Maikel J L NederkoornDepartment of Medical Oncology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Tom C P WalDepartment of Medical Oncology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.ORCID 0009-0003-8951-6256
Yvonne M H Versleijen-JonkersDepartment of Medical Oncology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-7623-0505
Pètra M BraamDepartment of Radiotherapy, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Uta E FluckeDepartment of Pathology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Johannes J BonenkampDepartment of Surgery, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Bart H W SchreuderDepartment of Orthopedics, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Carla M L van HerpenDepartment of Medical Oncology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Johannes H W de WiltDepartment of Surgery, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Ingrid M E DesarDepartment of Medical Oncology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Jacky W J de RooyDepartment of Radiology, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve local control, neoadjuvant radiotherapy (nRT) followed by surgery is the standard of care in myxofibrosarcoma (MFS) because of its infiltrative growth pattern. Nevertheless, local recurrence rates are high. Data on prognostic factors for poor clinical outcomes are lacking. This retrospective study thus investigates the prognostic relevance of magnetic resonance imaging (MRI) characteristics before and after nRT in 40 MFS patients, as well as their association with disease-free survival (DFS) and overall survival (OS). A vascular pedicle, defined as extra-tumoral vessels at the tumor periphery, was observed in 12 patients (30.0%) pre-nRT and remained present post-nRT in all cases. Patients with a vascular pedicle had worse DFS (HR 5.85; 95% CI 1.56-21.90;

Indexed as

local recurrencemagnetic resonance imagingmyxofibrosarcomaneoadjuvant radiotherapyprognostic factorssoft tissue sarcomatail signvascular pedicle

Identifiers

PMID37345181
PMCPMC10216260
OpenAlexW4377090958

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.