Evidence map›Paper›PMID 37345144›Full record

ArticleCancers2023

Voltage-Gated Sodium Channel Na

Piyasuda Pukkanasut, Jason Whitt, Rachael Guenter, Shannon E Lynch, Carlos Gallegos, Margarita Jacaranda Rosendo-Pineda, Juan Carlos Gomora, Herbert Chen, Diana Lin, Anna Sorace and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Piyasuda PukkanasutDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-0726-3060
Jason WhittDepartment of Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Rachael GuenterDepartment of Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Shannon E LynchGraduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-0325-2823
Carlos GallegosDepartment of Radiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Margarita Jacaranda Rosendo-PinedaDepartamento de Neuropatología Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-4955-8289
Juan Carlos GomoraDepartamento de Neuropatología Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-9871-1307
Herbert ChenDepartment of Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Diana LinDepartment of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.ORCID 0000-0002-3751-9514
Anna SoraceDepartment of Radiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-3640-3966
Renata Jaskula-SztulDepartment of Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Sadanandan E VeluDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-0342-2378
University of Alabama at Birmingham · USUniversidad Nacional Autónoma de México · MX

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Development and Functional Assessment of Cardiovascular Tissue Engineering Therapy (CVTE) T32 Training GrantT32EB023872 · NIBIB · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, JACK M, ZHANG, JIANYI · 2018 to 2022
$753k
Hydrogel encapsulated biofilm inhibitors for dental caries prevention and treatmentR21DE028349 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VELU, SADANANDAN E. · 2019 to 2020
$396k
Somatostatin receptor 2 (SSTR2) antibody-drug conjugate for pancreatic neuroendocrine tumor (PanNET) therapyR21CA226491 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JASKULA-SZTUL, RENATA, LIU, XIAOGUANG MARGARET · 2020 to 2021
$364k
NCI NIH HHS P30 CA013148NCI NIH HHS R21 CA226491NIBIB NIH HHS T32 EB023872NIDCR NIH HHS R21 DE028349NIH HHS R21CA226491, R21DE028349
6 · The paper itself

Abstract

Our results from quantitative RT-PCR, Western blotting, immunohistochemistry, and the tissue microarray of medullary thyroid cancer (MTC) cell lines and patient specimens confirm that VGSC subtype Na

Indexed as

cell invasioncell viabilitymedullary thyroid cancermetastasisNaV1.7neuroendocrine tumorvoltage-gated sodium channels

Identifiers

PMID37345144
PMCPMC10216335
OpenAlexW4377107399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.