Evidence map›Paper›PMID 37345036›Full record

ArticleCancers2023

Efficacy and Safety of High-Dose Chemotherapy with Treosulfan and Melphalan in Multiple Myeloma.

Cédric Gillich, Dilara Akhoundova, Michael Hayoz, Yolanda Aebi, Carlo R Largiadèr, Katja Seipel, Michael Daskalakis, Ulrike Bacher, Thomas Pabst

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Rising Prevalence of Low-FrequencyCurrent issues in molecular biology · 2024
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cédric GillichDepartment of Medical Oncology, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.
Dilara AkhoundovaDepartment of Medical Oncology, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-1639-3059
Michael HayozDepartment of Clinical Chemistry and Center for Laboratory Medicine, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.
Yolanda AebiDepartment of Clinical Chemistry and Center for Laboratory Medicine, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.
Carlo R LargiadèrDepartment of Clinical Chemistry and Center for Laboratory Medicine, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.
Katja SeipelDepartment of Medical Oncology, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-3128-1573
Michael DaskalakisDepartment of Hematology, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-8138-0505
Ulrike BacherDepartment of Hematology, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-8771-947X
Thomas PabstDepartment of Medical Oncology, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-6055-5257
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Upfront treatment consolidation with high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) has relevantly contributed to achieving durable remissions following induction treatment in multiple myeloma (MM) patients. The optimization of HDCT regimens can, therefore, essentially contribute to improving the depth and duration of tumor remissions. To date, melphalan at 200 mg/m

Indexed as

efficacyhigh riskmultiple myeloma (MM)overall survival (OS)pharmacokineticsprogression-free survival (PFS)response ratestandard risktreosulfan

Identifiers

PMID37345036
PMCPMC10216371
OpenAlexW4381598453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.