Evidence map›Paper›PMID 37345018›Full record

ArticleCancers2023

Synthesis of New Chromene Derivatives Targeting Triple-Negative Breast Cancer Cells.

Aysha Alneyadi, Zohra Nausheen Nizami, Hanan E Aburawi, Soleiman Hisaindee, Muhammad Nawaz, Samir Attoub, Gaber Ramadan, Nehla Benhalilou, Mazoun Al Azzani, Yassine Elmahi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Aysha AlneyadiDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Zohra Nausheen NizamiDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0003-2920-4173
Hanan E AburawiDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Soleiman HisaindeeDepartment of Chemistry, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Muhammad NawazDepartment of Nano-Medicine Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID 0000-0001-9016-9229
Samir AttoubDepartment of Pharmacology & Therapeutics, College of Medicine & Health Sciences, United Arab Emirates University, Al-Ain P.O. Box 15551, United Arab Emirates.
Gaber RamadanDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Nehla BenhalilouDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Mazoun Al AzzaniDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Yassine ElmahiDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Aysha AlmeqbaliDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Khalid MuhammadDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0001-6488-1722
Ali H EidDepartment of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3004-5675
Ranjit VijayanDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0002-3830-7409
Rabah IratniDepartment of Biology, College of Science, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0003-2694-0378
United Arab Emirates University · AEImam Abdulrahman Bin Faisal University · SAQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer continues to be the leading cause of cancer-related deaths among women worldwide. The most aggressive type of breast cancer is triple-negative breast cancer (TNBC). Indeed, not only does TNBC not respond well to several chemotherapeutic agents, but it also frequently develops resistance to various anti-cancer drugs, including taxane mitotic inhibitors. This necessitates the search for newer, more efficacious drugs. In this study, we synthesized two novel chromene derivatives (

Indexed as

apoptosischromenesmicrotubulesmitotic slippagemultinucleationsenescence

Identifiers

PMID37345018
PMCPMC10216081
OpenAlexW4376115930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.