Evidence map›Paper›PMID 37344962›Full record

ArticleDiabetes & vascular disease research

Can prediabetes diagnosed using HemoglobinA1c or oral glucose tolerance test predict presence and severity of coronary artery disease in symptomatic patients?

Katrine S Overgaard, Thomas R Andersen, Roda A Mohamed, Laurits J Heinsen, Helle G Binderup, Sören Möller, Søren Auscher, Jess Lambrechtsen, Kenneth Egstrup

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Katrine S OvergaardOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.ORCID 0000-0003-4445-8235
Thomas R AndersenOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.ORCID 0000-0003-0251-4489
Roda A MohamedOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.ORCID 0000-0003-0003-4801
Laurits J HeinsenOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.
Helle G BinderupOdense University Hospital, Department of Clinical Biochemistry, Svendborg, Denmark.
Sören MöllerOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.
Søren AuscherOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.
Jess LambrechtsenOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-9976-9981
Kenneth EgstrupOdense University Hospital Svendborg, Cardiovascular Research Unit, Svendborg, Denmark; University of Southern Denmark, Odense, Denmark.
University of Southern Denmark · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether prediabetes diagnosed by hemoglobinA1c (HbA1c) or oral glucose tolerance test (OGTT) could predict presence and severity of coronary artery disease (CAD) in symptomatic patients. The presence of plaque, stenosis, plaque characteristics, and coronary artery calcium (CAC) were evaluated by coronary CT angiography in 702 patients with suspicion of CAD. Patients were classified by glycemic status using the American Diabetes Association criteria for HbA1c and OGTT, and compared to their respective normal ranges. Prediabetes was observed in 24% by HbA1c and 72% by OGTT. Both prediabetes classifications were associated with increased presence of plaque, stenosis, calcified plaques, CAC >400, and a lower frequency of zero CAC compared to their respective normal range (all,

Indexed as

Coronary Artery DiseasePlaque, AtheroscleroticPrediabetic StateConstriction, PathologicCoronary AngiographyGlucose Tolerance TestGlycated HemoglobinHumansRisk FactorsGlycated HemoglobinAtherosclerosisChronic Coronary SyndromeCoronary Artery CalciumCoronary Artery DiseaseCoronary CT AngiographyHemoglobinA1cOral glucose tolerance testPrediabetes

Identifiers

PMID37344962
PMCPMC10288424
OpenAlexW4381597281

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.