Evidence map›Paper›PMID 37344744›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2023

Resuscitation outcomes in patients with cancer: experience in a large urban cancer centre.

Sabrina H M Yeung, Ramy Boles, Laveena Munshi, Mobolaji Moore, Sarah Seedon, Sumesh Shah, Santhosh Thyagu, Sangeeta Mehta

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Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sabrina H M Yeung *Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Ramy Boles *Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Laveena MunshiDepartment of Medicine, Sinai Health System, Interdepartmental Division of Critical Care Medicine, University of Toronto, 600 University Avenue Suite 18-216, Toronto, ON, M5G 1X5, Canada.
Mobolaji MooreDepartment of Medicine, Sinai Health System, Interdepartmental Division of Critical Care Medicine, University of Toronto, 600 University Avenue Suite 18-216, Toronto, ON, M5G 1X5, Canada.
Sarah SeedonDepartment of Medicine, Sinai Health System, Interdepartmental Division of Critical Care Medicine, University of Toronto, 600 University Avenue Suite 18-216, Toronto, ON, M5G 1X5, Canada.
Sumesh ShahDepartment of Medicine, Sinai Health System, Interdepartmental Division of Critical Care Medicine, University of Toronto, 600 University Avenue Suite 18-216, Toronto, ON, M5G 1X5, Canada.
Santhosh ThyaguPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Sangeeta MehtaDepartment of Medicine, Sinai Health System, Interdepartmental Division of Critical Care Medicine, University of Toronto, 600 University Avenue Suite 18-216, Toronto, ON, M5G 1X5, Canada. geeta.mehta@utoronto.ca.ORCID http://orcid.org/0000-0002-7073-4769
University of Toronto · CASinai Health System · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHospitalized patients with cancer who experience cardiopulmonary arrest have historically low survival rates. This retrospective cohort study describes outcomes of patients at a large Canadian cancer centre who had a "code medical emergency" activated, and the use of pragmatic criteria to identify patients with poor survival following resuscitation.

methodsWe included hospitalized patients with cancer who had a "code blue" activated between January 2007 and December 2018. Our primary outcome was intensive care unit (ICU) mortality. We developed pragmatic criteria to identify patients with "poor prognosis" for survival from cardiopulmonary resuscitation (CPR) based on disease status and candidacy for further cancer treatment. We used descriptive statistics to analyze the outcomes of poor prognosis patients.

resultsTwo hundred and twenty-five patients had a code blue activated. The median age was 61 yr, 52% were male, and 48% had a solid tumour. Overall, 173/225 (77%) patients survived the code blue; 164 were admitted to the ICU, where 49% (81/164) died; 31% survived to hospital discharge; and 16% (n = 27) were alive at one year. One hundred and twenty out of 225 (53%) required chest compressions; spontaneous circulation returned in 61% (73/120), and 12% (14/120) survived to hospital discharge. Patients meeting "poor prognosis" criteria (114, 51%) were more likely to die in the ICU (64% vs 35%; P < 0.001) or in hospital (86% vs 59%; P < 0.001), and more often had goals-of-care discussions prior to the code blue (46% vs 7%; P < 0.001). At one year, only 2% of poor prognosis patients were alive, compared with 24% of patients who did not meet any poor prognosis criteria.

conclusionHospitalized patients with cancer requiring CPR have poor hospital and long-term outcomes. The proposed set of pragmatic criteria may be useful to identify patients unlikely to benefit from CPR and life support, to trigger early goals of care discussions, and to avoid potentially goal-discordant interventions.

Indexed as

Cardiopulmonary ResuscitationHeart ArrestNeoplasmsCanadaFemaleHumansMaleMiddle AgedRetrospective Studiescancercardiac arrestoutcomes

Identifiers

PMID37344744
OpenAlexW4381486507

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.