Evidence map›Paper›PMID 37344731›Full record

ArticleJournal of autism and developmental disorders2024

Associations Between Autism Spectrum Quotient and Integration of Visual Stimuli in 9-year-old Children: Preliminary Evidence of Sex Differences.

Andrew E Silva, Jane E Harding, Arijit Chakraborty, Darren W Dai, Greg D Gamble, Christopher J D McKinlay, Samson Nivins, Rajesh Shah, Benjamin Thompson, Children with HYpoglycemia and their Later Development (CHYLD) Study Team

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Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Andrew E SilvaSchool of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada. andrew.silva@uwaterloo.ca.
Jane E HardingLiggins Institute, The University of Auckland, Auckland, New Zealand.
Arijit ChakrabortyChicago College of Optometry, Midwestern University, Downers Grove, IL, USA.
Darren W DaiLiggins Institute, The University of Auckland, Auckland, New Zealand.
Greg D GambleLiggins Institute, The University of Auckland, Auckland, New Zealand.
Christopher J D McKinlayLiggins Institute, The University of Auckland, Auckland, New Zealand.
Samson NivinsLiggins Institute, The University of Auckland, Auckland, New Zealand.
Rajesh ShahLiggins Institute, The University of Auckland, Auckland, New Zealand.
Benjamin ThompsonSchool of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada.
Children with HYpoglycemia and their Later Development (CHYLD) Study Team
University of Auckland · NZMidwestern University · USUniversity of Waterloo · CA

Funding

Health Research Council of New Zealand 17/240Maurice and Phyllis Paykel Trust Maurice and Phyllis Paykel Trust
6 · The paper itself

Abstract

purposeThe dorsal stream vulnerability hypothesis posits that the dorsal stream, responsible for visual motion and visuo-motor processing, may be particularly vulnerable during neurodevelopment. Consistent with this, autism spectrum disorder (ASD) has been associated with deficits in global motion integration, though deficits in ventral stream tasks, such as form identification, have also been reported. In the current study, we examined whether a similar pattern of results is found in a cohort of 381 children born with neurodevelopmental risk factors and exhibiting a wide spectrum of caregiver-reported autistic traits.

methodsWe examined the associations between global motion perception, global form perception, fine motor function, visual-motor integration, and autistic traits (autism spectrum quotient, AQ) using linear regression, accounting for possible interactions with sex and other factors relevant to neurodevelopment.

resultsAll assessments of dorsal stream function were significantly associated with AQ such that worse performance predicted higher AQ scores. We also observed a significant sex interaction, with worse global form perception associated with higher AQ in boys (n = 202) but not girls (n = 179).

conclusionWe found widespread associations between dorsal stream functions and autistic traits. These associations were observed in a large group of children with a range of AQ scores, demonstrating a range of visual function across the full spectrum of autistic traits. In addition, ventral function was associated with AQ in boys but not girls. Sex differences in the associations between visual processing and neurodevelopment should be considered in the designs of future studies.

Indexed as

Autism Spectrum DisorderChildFemaleHumansMaleMotion PerceptionPhotic StimulationPsychomotor PerformanceSex CharacteristicsSex FactorsVisual PerceptionAutism Spectrum QuotientAutistic TraitsDorsal Stream VulnerabilitySex DifferencesVisual IntegrationVisual-Motor Integration

Identifiers

PMID37344731
OpenAlexW4381488800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.